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Symbol
Name
ID

Cyp11b2
cytochrome P450, family 11, subfamily b, polypeptide 2
MGI:88584

Phenotype annotations related to cardiovascular system

Darker colors indicate more annotations

Human Phenotypes	Dilated cardiomyopathy	Hypotension	Orthostatic hypotension	Elevated diastolic blood pressure	Elevated systolic blood pressure	Hypertension	Hypovolemia	Abnormality of the hepatic vasculature	Hepatosplenomegaly
Disease(s) Associated with CYP11B1	Dilated cardiomyopathy	Hypotension	Orthostatic hypotension	Elevated diastolic blood pressure	Elevated systolic blood pressure	Hypertension	Hypovolemia	Abnormality of the hepatic vasculature	Hepatosplenomegaly
congenital adrenal hyperplasia
glucocorticoid-remediable aldosteronism
primary hyperaldosteronism
Disease(s) Associated with CYP11B2
corticosterone methyloxidase deficiency 1
dilated cardiomyopathy 1H
pre-eclampsia
primary hyperaldosteronism

Mouse Phenotypes		increased myocardial fiber size	increased heart weight	cardiac fibrosis	hypotension	increased systemic arterial blood pressure	increased systemic arterial systolic blood pressure
Availability	Mouse Genotype	increased myocardial fiber size	increased heart weight	cardiac fibrosis	hypotension	increased systemic arterial blood pressure	increased systemic arterial systolic blood pressure
	Cyp11b1^tm1Chjk/Cyp11b1^tm1Chjk
	Cyp11b2^tm1Hsk/Cyp11b2^tm1Hsk
	Cyp11b2^tm2Hsk/Cyp11b2^tm2Hsk

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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