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Symbol
Name
ID
En2
engrailed 2
MGI:95390
Phenotype annotations related to behavior/neurological
Darker colors indicate more annotations
Human Phenotypes
Lack of spontaneous play
Impaired ability to form peer relationships
Autism
Inflexible adherence to routines
Motor stereotypy
Restrictive behavior
Disease(s) Associated with EN2
autistic disorder

Mouse Phenotypes
abnormal behavior
abnormal spatial learning
decreased aggression towards mice
abnormal grooming behavior
decreased grooming behavior
increased grooming behavior
abnormal motor capabilities/coordination/movement
impaired righting response
abnormal motor coordination/balance
impaired coordination
abnormal grip strength
abnormal locomotor activation
hyperactivity
abnormal social/conspecific interaction behavior
abnormal social investigation
Availability Mouse Genotype
En2tm1Alj/En2tm1Alj
En2tm1Alj/En2+

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory