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Symbol
Name
ID
Tbp
TATA box binding protein
MGI:101838
Phenotype annotations related to behavior/neurological
Darker colors indicate more annotations
Human Phenotypes
Urinary incontinence
Depression
Low frustration tolerance
Apathy
Negativism
Personality changes
Polydipsia
Polyphagia
Aggressive behavior
Impulsivity
Agitation
Weak voice
Disease(s) Associated with TBP
late onset Parkinson's disease
schizophrenia
spinocerebellar ataxia type 17
type 1 diabetes mellitus

Mouse Phenotypes
impaired balance
impaired coordination
hunched posture
abnormal gait
short stride length
decreased locomotor activity
abnormal nest building behavior
Availability Mouse Genotype
Tbptm1Xjl/Tbptm1Xjl
Tg(Nes-cre)1Kln/?  (conditional)
Tbptm1Xjl/Tbp+
Tg(CAG-cre/Esr1*)5Amc/0  (conditional)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory