Excel File Text File All mouse models of amyloidosis with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      transthyretin amyloidosis Rbp4tm1(RBP4)Zhel/Rbp4tm1(RBP4)Zhel
Ttrtm2(TTR)Kymm/Ttrtm2(TTR)Kymm
B6.Cg-Ttrtm2(TTR)Kymm Rbp4tm1(RBP4)Zhel J:260683 View
transthyretin amyloidosis Rbp4tm1(RBP4)Zhel/Rbp4tm1(RBP4)Zhel
Ttrtm2(TTR)Kymm/Ttrtm3(TTR*)Kymm
Not Specified J:260683 View
transthyretin amyloidosis Tg(TTR)#Jbux/0 involves: C57BL/6 * DBA/2 J:68458 View
transthyretin amyloidosis Ttrtm1.1Smoc/? involves: C57BL/6J * C57BL/6N J:257096 View
      cerebral amyloid angiopathy Itm2btm1.1Ldad/Itm2b+ B6.129-Itm2btm1.1Ldad J:167154 View
cerebral amyloid angiopathy Itm2btm1.1Ldad/Itm2btm1.1Ldad involves: 129 J:166696 View
cerebral amyloid angiopathy Itm2btm2.1Ldad/Itm2b+ B6.129-Itm2btm2.1Ldad J:167154 View
cerebral amyloid angiopathy Itm2btm3.1Ldad/Itm2btm3.1Ldad B6.129-Itm2btm3.1Ldad J:166696 View
Transgenes and
Other Mutations
     amyloidosis Tg(CMV-IGL@AL080)55Dcs/0 involves: FVB J:179082 View
amyloidosis Tg(H2-L-IL6)46Kish/Tg(H2-L-IL6)46Kish C.B6-Tg(H2-L-IL6)46Kish J:177820 View
amyloidosis Tg(Ly6a-GCSAM)102AIsg/0 involves: C57BL/6J * CBA J:221238 View
amyloidosis Tg(Mt1-IL6)28Gci/0 involves: C57BL/6 * DBA/2 J:177825 View
cerebral amyloid angiopathy Abcc1tm1Bor/Abcc1tm1Bor
Tg(Thy1-APPDutch)#Jckr/0
FVB.Cg-Abcc1tm1Bor Tg(Thy1-AppDutch)#Jckr J:178230 View
cerebral amyloid angiopathy Tg(APPswe,PSEN1dE9)85Dbo/0 CAST.Cg-Tg(APPswe,PSEN1dE9)85Dbo/How J:276728 View
cerebral amyloid angiopathy Tg(APPswe,PSEN1dE9)85Dbo/0 WSB.Cg-Tg(APPswe,PSEN1dE9)85Dbo/How J:276728 View
cerebral amyloid angiopathy Tg(Prnp-APPSweArc)#Rmni/0 involves: C57BL/6 * DBA/2 J:203724 View
cerebral amyloid angiopathy Tg(Prnp-ITM2B*)1Ruvi/? B6.C3Fe-Tg(Prnp-ITM2B*)1Ruvi J:155720 View
cerebral amyloid angiopathy Tg(Prnp-ITM2B*)1Ruvi/Tg(Prnp-ITM2B*)1Ruvi involves: C3HeB/FeJ * C57BL/6 J:197198 View
cerebral amyloid angiopathy Tg(Prnp-ITM2B*)1Ruvi/Tg(Prnp-ITM2B*)1Ruvi
Tg(Prnp-MAPT*P301L)#Ruvi/Tg(Prnp-MAPT*P301L)#Ruvi
involves: C3HeB/FeJ * C57BL/6 J:197198 View
cerebral amyloid angiopathy Tg(Prnp-ITM2B*)7Jckr/0 C57BL/6-Tg(Prnp-ITM2B*)7Jckr J:159279 View
cerebral amyloid angiopathy Tg(Thy1-APP)3Somm/0 involves: C57BL/6J * DBA/2 J:67583 View
cerebral amyloid angiopathy Tg(Thy1-APPDutch)#Jckr/0 involves: C57BL/6J J:92796, J:162531 View
cerebral amyloid angiopathy Tg(Thy1-APPDutch)#Jckr/0
Tg(Thy1-BACE1)54/4Ppa/0
involves: C57BL/6 J:162531 View
cerebral amyloid angiopathy Tg(Thy1-APPDutch)#Jckr/0
Tg(Thy1-PSEN1*G384A)45Jckr/0
involves: C57BL/6 * C57BL/6J * DBA/2 J:92796 View
cerebral amyloid angiopathy Tg(Thy1-APPSwDutIowa)BWevn/0 involves: C57BL/6 J:89848 View
cerebral amyloid angiopathy Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz/0 C57BL/6-Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz J:165986 View
cerebral amyloid angiopathy Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz/0
Tg(Thy1-MAPT)183Gotz/0
B6.Cg-Tg(Thy1-APPSwe,Prnp-PSEN2*N141I)152HLaoz Tg(Thy1-MAPT)183Gotz J:154968 View
Finnish type amyloidosis Tg(Ckm-GSN*D187N)AJewe/0 C57BL/6J-Tg(Ckm-GSN*D187N)AJewe J:150825 View
Finnish type amyloidosis Tg(Ckm-GSN*D187N)AJewe/Tg(Ckm-GSN*D187N)AJewe C57BL/6J-Tg(Ckm-GSN*D187N)AJewe J:150825 View
transthyretin amyloidosis Hsf1tm1Ijb/Hsf1tm1Ijb
Tg(TTR-V30M)15Imeg/0
involves: 129S6/SvEvTac * BALB/c * C57BL/6 J:156658 View
transthyretin amyloidosis Tg(TTR-V30M)15Imeg/0 involves: C57BL/6 J:260683 View
transthyretin amyloidosis Tg(TTR-V30M)15Imeg/0 Not Specified J:80880 View
Additional
Complex
Models
     cerebral amyloid angiopathy Lrp1tm2Her/Lrp1tm2Her
Tg(APP695)3Dbo/0
Tg(PSEN1)5Dbo/0
Tg(Tagln-cre)1Her/0
involves: 129S7/SvEvBrd * C3H/HeJ * C57BL/6 * C57BL/6J * SJL J:192453 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      cerebral amyloid angiopathy Itm2btm2.1Ldad/Itm2btm2.1Ldad B6.129-Itm2btm2.1Ldad J:155411 View