Phenotypes Associated with This Genotype

Genotype
MGI:6194720

• Allelic Composition: Ttr^tm1.1Smoc/?
• Genetic Background: involves: C57BL/6J * C57BL/6N

• ♀: phenotype observed in females
• ♂: phenotype observed in males
• N: normal phenotype

vision/eye

increased opacity of vitreous body ( J:257096 )

• all mice exhibit vitreous opacities by about 6 months of age

vitreous body deposition ( J:257096 )

• some mice exhibit amyloid deposition in the vitreous

homeostasis/metabolism

amyloidosis ( J:257096 )

• some mice exhibit amyloid deposition in the vitreous only

• no amyloid deposition is seen in the kidneys, hearts, or brains

Mouse Models of Human Disease		DO ID	OMIM ID(s)	Ref(s)
hereditary systemic amyloidosis 1		DOID:0050638	OMIM:105210	J:257096