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Phenotypes Associated with This Genotype
Genotype
MGI:4415612
Allelic
Composition		 Itm2btm2.1Ldad/Itm2btm2.1Ldad
Genetic
Background		 B6.129-Itm2btm2.1Ldad
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Itm2btm2.1Ldad mutation (0 available); any Itm2b mutation (18 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype

Signs of melanosis in the meninges of the olfactory bulb and mineralization in the thalamus of Itm2btm2.1Ldad/Itm2btm2.1Ldad mice

nervous system
nervous system phenotype ( J:155411 )
N
• absence of expected amyloid lesion

Mouse Models of Human Disease
 DO ID OMIM ID(s) Ref(s)
NOT cerebral amyloid angiopathy DOID:9246 J:155411

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
09/30/2025
MGI 6.24 		The Jackson Laboratory