Rbp4tm1(RBP4)Zhel
Targeted Allele Detail
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Symbol: |
Rbp4tm1(RBP4)Zhel |
Name: |
retinol binding protein 4, plasma; targeted mutation 1, Zhenghua Li |
MGI ID: |
MGI:5749289 |
Synonyms: |
hVal30:hRBP4, mRbp4hRBP4 |
Gene: |
Rbp4 Location: Chr19:38105077-38113729 bp, - strand Genetic Position: Chr19, 32.75 cM, cytoband D1
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Alliance: |
Rbp4tm1(RBP4)Zhel page
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Allele Type: |
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Targeted (Humanized sequence, Inserted expressed sequence, RMCE-ready) |
Mutation: |
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Insertion
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Rbp4tm1(RBP4)Zhel expresses
1 gene
Knock-in expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
RBP4 (5950) |
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Mutation details: ES cells containing the Rbp4tm2Zhel null allele that serves as an acceptor in recombination mediated cassette exchange were electroporated with a replacement vector and a cre recombinase expression vector. The replacement vector consisted of a wild-type human RBP4 cDNA and a FRT-flanked puromycin resistance gene flanked by a loxKMR3 and a loxP site.
(J:220321, J:260683)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Rbp4 Mutation: |
19 strains or lines available
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Original: |
J:220321 Mu Y, et al., CHF5074 (CSP-1103) stabilizes human transthyretin in mice humanized at the transthyretin and retinol-binding protein loci. FEBS Lett. 2015 Mar 24;589(7):849-56 |
All: |
2 reference(s) |
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