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Phenotypes Associated with This Genotype
Genotype
MGI:3613376
Allelic
Composition
Tg(TTR-V30M)15Imeg/0
Genetic
Background
Not Specified
Find Mice Using the International Mouse Strain Resource (IMSR)
No mouse lines available in IMSR.
See publication links below for author information.
phenotype observed in females
phenotype observed in males
N normal phenotype
homeostasis/metabolism
• amyloid deposition starts in the gastrointestinal tract, cardiovascular system, and kidneys 6 months after birth and extends to various other organs and tissues with advancing age
• however, amyloid does not accumulate in the choroid plexus and in the peripheral and autonomic nervous systems

Mouse Models of Human Disease
DO ID OMIM ID(s) Ref(s)
transthyretin amyloidosis DOID:0050638 OMIM:105210
J:80880


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/19/2024
MGI 6.23
The Jackson Laboratory