Excel File Text File All mouse models of cerebrovascular disease with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      arteriovenous malformations of the brain \Engtm2.1Hma/\Engtm2.1Hma involves: 129P2/OlaHsd J:196810 View
arteriovenous malformations of the brain \Krastm4Tyj/\Kras+
\Tg(Cdh5-cre/ERT2)1Rha/0
involves: 129S4/SvJae * FVB J:312482 View
arteriovenous malformations of the brain \Krastm4Tyj/\Kras+
\Tg(Slco1c1-icre/ERT2)1Mash/0
involves: 129S4/SvJae * C57BL/6 * DBA/2 * FVB J:312482 View
cerebral cavernous malformation \Krit1tm1Kwhi/\Krit1tm1Kwhi
\Tg(Cdh5-cre/ERT2)1Rha/0
involves: 129S6/SvEvTac * C57BL/6NCrl J:232707, J:250906 View
cerebral cavernous malformation 2 \Ccm2tm1.1Etl/\Ccm2tm1Etl
\Tg(Cdh5-cre/ERT2)1Rha/0
involves: 129 * C57BL/6 J:177584 View
cerebral cavernous malformation 2 \Ccm2tm1Kwhi/\Ccm2tm1.1Kwhi
\Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/?
involves: C57BL/6 * CBA J:173947 View
cerebral cavernous malformation 2 \Ccm2tm1Mlkn/\Ccm2tm1Mlkn
\Tg(Cdh5-cre/ERT2)1Rha/0
involves: 129 J:250906 View
cerebral cavernous malformation 2 \Ccm2tm2.1Sbn/\Ccm2tm2.1Sbn
\Tg(Mx1-cre)1Cgn/0
involves: C57BL/6 * CBA J:174085 View
cerebral cavernous malformation 3 \Pdcd10tm1Kwhi/\Pdcd10tm1.1Kwhi
\Tg(Pdgfb-icre/ERT2,-EGFP)1Frut/?
involves: C57BL/6 * CBA J:173947 View
cerebral cavernous malformation 3 \Pdcd10tm1Wami/\Pdcd10tm1Wami
\Tg(GFAP-cre)25Mes/0
involves: 129 * C57BL/6 * FVB/N J:170480 View
      arteriovenous malformations of the brain \Acvrl1tm2.1Spo/\Acvrl1tm2.1Spo involves: 129 J:196810 View
arteriovenous malformations of the brain \Tg(Tek-tTA)1Rwng/0
\Tg(tetO-Notch4*)1Rwng/0
involves: FVB/N J:139943 View
Transgenes and
Other Mutations
     brain ischemia \Tg(Notch3*R169C)88Bbb/0 involves: FVB/N J:156682 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      cerebral cavernous malformation 2 \Ccm2tm1Etl/\Ccm2tm1Etl
\Tg(Nes-cre)1Kln/?
B6.Cg-Ccm2tm1Etl Tg(Nes-cre)1Kln J:146210 View
cerebral cavernous malformation 2 \Ccm2tm2.1Sbn/\Ccm2tm2.1Sbn
\Tg(Tek-cre)1Ywa/0
involves: C57BL/6 * SJL J:174085 View
Moyamoya disease \Rnf213tm1.1Mfuji/\Rnf213tm1.1Mfuji involves: C57BL/6 J:229422 View