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All mouse models of heart valve disease with phenotypic similarity to the human disease
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| Disease Term | Allelic Composition | Genetic Background | Reference | Phenotypes | ||||
  | mitral valve prolapse | \Dchs1tm1.2Irv/\Dchs1+ | involves: 129S7/SvEvBrd * C57BL/6 | J:225789 | View | |||
| mitral valve prolapse | \Dzip1em1Sasl/\Dzip1+ | C57BL/6J-Dzip1em1Sasl | J:291454 | View | ||||
| mitral valve prolapse |
\Dzip1tm1Sasl/\Dzip1tm1Sasl \Nfatc1tm1.1(cre)Bz/\Nfatc1+ |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:291454 | View | ||||
| supravalvular aortic stenosis | \Elntm1Dyl/\Eln+ | B6.129-Elntm1Dyl | J:86535 | View | ||||
| supravalvular aortic stenosis | \Elntm1Dyl/\Eln+ | involves: 129S1/Sv * 129X1/SvJ * C57BL/6J | J:51109 | View | ||||
| | aortic valve disease | \Adamts19tm4a(EUCOMM)Wtsi/\Adamts19tm4a(EUCOMM)Wtsi | C57BL/6N-Adamts19tm4a(EUCOMM)Wtsi | J:287334 | View | |||
| aortic valve disease | \Adamts19tm4b(EUCOMM)Wtsi/\Adamts19tm4b(EUCOMM)Wtsi | B6N(Cg)-Adamts19tm4b(EUCOMM)Wtsi | J:287334 | View | ||||
| aortic valve disease | \Egfrwa2/\Egfrwa2 | involves: C57BL/6 | J:241813 | View | ||||
| aortic valve disease | \Egfrwa2/\Egfrwa2 | STOCK Egfrwa2 | J:60750 | View | ||||
| aortic valve disease | \Elntm1Dyl/\Eln+ | involves: 129S1/Sv * 129X1/SvJ * C57BL/6 | J:184494 | View | ||||
| aortic valve disease | \Hey2tm1Kkb/\Hey2tm1Kkb | involves: 129S7/SvEvBrd * C57BL/6 | J:216895 | View | ||||
| aortic valve disease | \Nos3tm1Unc/\Nos3tm1Unc | B6.129P2-Nos3tm1Unc/J | J:103340 | View | ||||
| aortic valve disease | \Rbpjtm1Kyo/\Rbpj+ | involves: 129S2/SvPas * CD-1 | J:187551 | View | ||||
| aortic valve stenosis | \Tnftm2Gkl/\Tnf+ | involves: 129S/SvEv * C57BL/6J | J:264147 | View | ||||
| Ebstein anomaly |
\Bmpr1atm1Bhr/\Bmpr1atm2.1Bhr \Tg(GATA6-cre)#Jbeb/0 |
involves: 129S7/SvEvBrd * C57BL/6 * FVB | J:111392 | View | ||||
| heart valve disease | \Galnt1tm1.1Jxm/\Galnt1tm1.1Jxm | B6NHsd.Cg-Galnt1tm1.1Jxm | J:242253 | View | ||||
| heart valve disease | \TnfBpsm1/\Tnf+ | C.Cg-TnfBpsm1 | J:226052 | View | ||||
| mitral valve disease |
\Ift88tm1Bky/\Ift88tm1Bky \Nfatc1tm1.1(cre)Bz/\Nfatc1+ |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ | J:291454 | View | ||||
| tricuspid atresia | \Zfpm2tm1Jml/\Zfpm2tm1Jml | involves: 129X1/SvJ | J:63121 | View | ||||
| Additional Complex Models | aortic valve disease |
\Apobtm2Sgy/\Apobtm2Sgy \Ldlrtm1Her/\Ldlrtm1Her \Tg(Ins-Igf2)1Fbos/? |
involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J * SJL | J:227165 | View | |||
| mitral valve disease |
\H2b/\H2g7 \Tg(TcraR28,TcrbR28)KRNDim/0 |
involves: C57BL/6 * NOD * SJL | J:275827 | View | ||||