Excel File Text File All mouse models of squamous cell carcinoma with phenotypic similarity to the human disease
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
      skin squamous cell carcinoma \Tg(KRT14-Fyn*)aJsey/0 involves: C57BL/6 * CBA * FVB/N J:155536 View
      squamous cell carcinoma \Dicer1tm1Snj/\Dicer1tm1Snj
\Trp53tm1Brn/\Trp53tm1Brn
\Tg(KRT5-cre/PGR)1Der/0
involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6N * FVB/N * ICR J:216813 View
squamous cell carcinoma \Krastm4Tyj/\Kras+
\Trp53tm1Brn/\Trp53tm1Brn
\Tg(KRT14-cre/ERT)20Efu/0
involves: 129P2/OlaHsd * 129S4/SvJae * CD-1 J:172048 View
Transgenes and
Other Mutations
     adenosquamous lung carcinoma \Tg(Scgb1a1-rtTA)1Jaw/0
\Tg(tetO-ERBB2*)5BKkw/0
involves: FVB/N J:143874 View
adenosquamous lung carcinoma \Tg(Scgb1a1-rtTA)1Jaw/0
\Tg(tetO-ERBB2*)26Kkw/0
involves: FVB/N J:143874 View
skin squamous cell carcinoma \Tg(KRT14-HPV16)wt1Dh/0 either: FVB.Cg-Tg(KRT14-HPV16)wt1Dh or (involves: C57BL/6 * DBA/2 * FVB/N) J:20130 View
Additional
Complex
Models
     head and neck squamous cell carcinoma \Ptentm1Hwu/\Ptentm1Hwu
\Tgfbr1tm1.1Karl/\Tgfbr1tm1.1Karl
\Tg(KRT14-cre/ERT)20Efu/0
involves: 129 * 129S4/SvJae * C57BL/6 * CD-1 * FVB/N J:194652 View
head and neck squamous cell carcinoma \Tg(KRT14-cre)8Brn/0
\Tg(KRT5-Akt1*)Jmpa/0
\Trp53tm1Brn/\Trp53tm1Brn
involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * DBA/2J * FVB/N J:144831 View
lung squamous cell carcinoma \Nr1h2tm1.1Gstr/\Nr1h2tm1.1Gstr
\Nr1h3tm1.1Gstr/\Nr1h3tm1.1Gstr
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 J:234268 View
squamous cell carcinoma \Krastm4Tyj/\Kras+
\Smad4tm2.1Cxd/\Smad4tm2.1Cxd
\Tg(Krt1-15-cre/PGR*)22Cot/0
involves: 129S4/SvJae * 129S6/SvEvTac * C57BL/6 * C57BL/6J * SJL/J J:203922 View


       
No similarity to the expected human disease phenotype was found.
        Disease Term Allelic Composition Genetic Background Reference Phenotypes
NOT Models      skin squamous cell carcinoma \Tg(KRT14-HPV16)wt1Dh/0 C.Cg-Tg(KRT14-HPV16)wt1Dh J:20130 View
skin squamous cell carcinoma \Tg(KRT14-HPV16)wt1Dh/0 either: (involves: C57BL/6 * DBA/2) or (involves: C57BL/6 * DBA/2 * SENCAR * SSIN) J:20130 View