			Excel File Text File Disease is associated/modeled with this Gene* or a homolog. More...
			Disease Term	Human Homologs	Mouse Homologs	Mouse Models	Homology Source
			buphthalmos	CYP1B1*	Cyp1b1*	4 models	Alliance of Genome Resources
			exfoliation syndrome	LOXL1*	Loxl1*	1 model	Alliance of Genome Resources
			low tension glaucoma	OPTN*	Optn*	1 model	Alliance of Genome Resources
			angle-closure glaucoma	TFAP2B	Tfap2b*	1 model	Alliance of Genome Resources
			buphthalmos	FOXC1	Foxc1*	2 models	Alliance of Genome Resources
			buphthalmos	TYR	Tyr*	3 models	Alliance of Genome Resources
			exfoliation syndrome	LYST	Lyst*	1 model	Alliance of Genome Resources
			glaucoma	PITX2	Pitx2*	1 model	Alliance of Genome Resources
			glaucoma	METTL23	Mettl23*	4 models	Alliance of Genome Resources
			glaucoma	LGR4	Lgr4*	1 model	Alliance of Genome Resources
			glaucoma	SH3PXD2B	Sh3pxd2b*	1 model	Alliance of Genome Resources
			juvenile glaucoma	PAX6	Pax6*	1 model	Alliance of Genome Resources
			low tension glaucoma	SLC1A1	Slc1a1*	1 model	Alliance of Genome Resources
			low tension glaucoma	SOD1	Sod1*	1 model	Alliance of Genome Resources
			low tension glaucoma	SLC1A3	Slc1a3*	1 model	Alliance of Genome Resources
			primary open angle glaucoma	GUCY1A1	Gucy1a1*	1 model	Alliance of Genome Resources
			angle-closure glaucoma	MTHFR*	Mthfr		Alliance of Genome Resources
			angle-closure glaucoma	GSTM1*, GSTM5	Gstm1, Gstm2, Gstm3, Gstm6		Alliance of Genome Resources
			angle-closure glaucoma	NOS3*	Nos3		Alliance of Genome Resources
			angle-closure glaucoma	APOE*	Apoe		Alliance of Genome Resources
			angle-closure glaucoma	HGF*	Hgf		Alliance of Genome Resources
			angle-closure glaucoma	MMP9*	Mmp9		Alliance of Genome Resources
			angle-closure glaucoma	CAT*	Cat		Alliance of Genome Resources
			exfoliation syndrome	APOE*	Apoe		Alliance of Genome Resources
			exfoliation syndrome	GSTM1*, GSTM5	Gstm1, Gstm2, Gstm3, Gstm6		Alliance of Genome Resources
			exfoliation syndrome	GSTT1*	Gstt1		Alliance of Genome Resources
			exfoliation syndrome	TLR4*	Tlr4		Alliance of Genome Resources
			exfoliation syndrome	ACVR1*	Acvr1		Alliance of Genome Resources
			exfoliation syndrome	CLU*	Clu		Alliance of Genome Resources
			glaucoma	EEF2*	Eef2		Alliance of Genome Resources
			glaucoma	BDNF*	Bdnf		Alliance of Genome Resources
			glaucoma	AGO2*	Ago2		Alliance of Genome Resources
			glaucoma	WDR36*	Wdr36		Alliance of Genome Resources
			glaucoma	OPTN*	Optn		Alliance of Genome Resources
			glaucoma	LINGO1*	Lingo1		Alliance of Genome Resources
			glaucoma	HLA-DRB1*, HLA-DRB3, HLA-DRB4, HLA-DRB5	H2-Eb1, H2-Eb2		Alliance of Genome Resources
			glaucoma	HLA-DQB1*, HLA-DQB2	H2-Ab1		Alliance of Genome Resources
			glaucoma	FOXC1*	Foxc1		Alliance of Genome Resources
			glaucoma	EPO*	Epo		Alliance of Genome Resources
			glaucoma	CNTF*	Cntf		Alliance of Genome Resources
			hydrophthalmos	CYP1B1*	Cyp1b1		Alliance of Genome Resources
			juvenile glaucoma	MYOC*	Myoc		Alliance of Genome Resources
			low tension glaucoma	ADRB1*	Adrb1		Alliance of Genome Resources
			low tension glaucoma	APOE*	Apoe		Alliance of Genome Resources
			low tension glaucoma	CAV2*	Cav2		Alliance of Genome Resources
			low tension glaucoma	MYOC*	Myoc		Alliance of Genome Resources
			low tension glaucoma	TLR4*	Tlr4		Alliance of Genome Resources
			low tension glaucoma	TNF*	Tnf		Alliance of Genome Resources
			low tension glaucoma	TP53*	Trp53		Alliance of Genome Resources
			open-angle glaucoma	ADRB2*	Adrb2		Alliance of Genome Resources
			open-angle glaucoma	AFAP1*	Afap1		Alliance of Genome Resources
			open-angle glaucoma	APOE*	Apoe		Alliance of Genome Resources
			open-angle glaucoma	CDKN2B*	Cdkn2b		Alliance of Genome Resources
			open-angle glaucoma	GMDS*	Gmds		Alliance of Genome Resources
			open-angle glaucoma	MEIS2*	Meis2		Alliance of Genome Resources
			open-angle glaucoma	MTHFR*	Mthfr		Alliance of Genome Resources
			open-angle glaucoma	MYOC*	Myoc	1 model	Alliance of Genome Resources
			open-angle glaucoma	OPTN*	Optn		Alliance of Genome Resources
			open-angle glaucoma	PON1*	Pon1		Alliance of Genome Resources
			open-angle glaucoma	TAP1*	Tap1		Alliance of Genome Resources
			open-angle glaucoma	TNF*	Tnf		Alliance of Genome Resources
			primary angle-closure glaucoma	ACVR1*	Acvr1		Alliance of Genome Resources
			primary angle-closure glaucoma	MYRF*	Myrf		Alliance of Genome Resources
			primary angle-closure glaucoma	COL18A1*	Col18a1		Alliance of Genome Resources
			primary open angle glaucoma	TNF*	Tnf		Alliance of Genome Resources
			primary open angle glaucoma	TLR4*	Tlr4		Alliance of Genome Resources
			primary open angle glaucoma	THBS1*	Thbs1		Alliance of Genome Resources
			primary open angle glaucoma	SOD2*	Sod2		Alliance of Genome Resources
			primary open angle glaucoma	PON1*	Pon1		Alliance of Genome Resources
			primary open angle glaucoma	OPTN*	Optn		Alliance of Genome Resources
			primary open angle glaucoma	OGG1*	Ogg1		Alliance of Genome Resources
			primary open angle glaucoma	ADIPOQ*	Adipoq		Alliance of Genome Resources
			primary open angle glaucoma	ACVR1*	Acvr1		Alliance of Genome Resources
			primary open angle glaucoma	NOS3*	Nos3		Alliance of Genome Resources
			primary open angle glaucoma	MYOC*	Myoc		Alliance of Genome Resources
			primary open angle glaucoma	MMP1*	Mmp1a, Mmp1b		Alliance of Genome Resources
			primary open angle glaucoma	LOXL1*	Loxl1		Alliance of Genome Resources
			primary open angle glaucoma	LAMB2*	Lamb2		Alliance of Genome Resources
			primary open angle glaucoma	GSTT1*	Gstt1		Alliance of Genome Resources
			primary open angle glaucoma	GSTM1*, GSTM5	Gstm1, Gstm2, Gstm3, Gstm6		Alliance of Genome Resources
primary open angle glaucoma	ESR2*	Esr2		Alliance of Genome Resources
primary open angle glaucoma	CYP1B1*	Cyp1b1		Alliance of Genome Resources
primary open angle glaucoma	COL6A3*	Col6a3		Alliance of Genome Resources
primary open angle glaucoma	CDKN1A*	Cdkn1a		Alliance of Genome Resources
primary open angle glaucoma	CAV2*	Cav2		Alliance of Genome Resources
primary open angle glaucoma	CAV1*	Cav1		Alliance of Genome Resources
primary open angle glaucoma	APOE*	Apoe		Alliance of Genome Resources
primary open angle glaucoma	ADRB2*	Adrb2		Alliance of Genome Resources
primary open angle glaucoma	WDR36*	Wdr36		Alliance of Genome Resources
primary open angle glaucoma	TP53*	Trp53		Alliance of Genome Resources

Transgenes and other genome features developed in mice to model this disease.

Disease Term Transgenes and Other Genome Features Mouse Models

low tension glaucoma Tg(TBK1)#Andm 2 models

open-angle glaucoma Tg(Myoc*Y423H)#Sit 1 model

open-angle glaucoma Tg(MYOC*Y437H)#Sit 1 model

primary open angle glaucoma Tg(CMV-MYOC*Y437H)#Vcs 1 model

primary open angle glaucoma Tg(OPTN*E50K,-EGFP)1Mde 1 model

Transgenes and other genome features developed in mice to model this disease.
Disease Term	Transgenes and Other Genome Features	Mouse Models
low tension glaucoma	Tg(TBK1)#Andm	2 models
open-angle glaucoma	Tg(Myoc*Y423H)#Sit	1 model
open-angle glaucoma	Tg(MYOC*Y437H)#Sit	1 model
primary open angle glaucoma	Tg(CMV-MYOC*Y437H)#Vcs	1 model
primary open angle glaucoma	Tg(OPTN*E50K,-EGFP)1Mde	1 model