Werner syndrome (DOID:5688)
Alliance: disease page
Synonyms: adult premature ageing syndrome; adult progeria; Werner's syndrome; WS
Alt IDs: OMIM:277700, MESH:D014898, NCI:C3447, ORDO:902, UMLS_CUI:C0043119
Definition: A syndrome characterized by premature aging and age-related phenotypes such as atherosclerosis, arteriosclerosis, cataracts, osteoporosis, soft tissue calcification, premature thinning, graying, and loss of hair, as well as a high incidence of some types of cancers and that has_material_basis_in mutations in the WRN gene, on chromosome 8.