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Gene Expression Data
Assay Details
Assay
Reference: J:272602 Shigeta A, et al., Endocardially Derived Macrophages Are Essential for Valvular Remodeling. Dev Cell. 2019 Mar 11;48(5):617-630.e3
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8406226
Gene symbol: Adgre1
Gene name: adhesion G protein-coupled receptor E1
Antibody: anti-F4/80 (MCA497R)
Detection system: Secondary antibody
Results
Specimen 3I: embryonic day 15.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Nfatc1tm1.1(cre)Bz/Nfatc1+ (more )
Note: Conditional mutant. Double labeled: red - Adgre1; green - reporter.
Structure Cell Type Level Pattern Image Note
TS23: endocardial cushion macrophage Present 3I

Specimen 3M: postnatal day 1; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Nfatc1tm1.1(cre)Bz/Nfatc1+ (more )
Note: Conditional mutant. Double labeled: red - Adgre1; green - reporter.
Structure Cell Type Level Pattern Image Note
TS27: heart valve macrophage Present 3M

Specimen 3Q: postnatal day 8; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Nfatc1tm1.1(cre)Bz/Nfatc1+ (more )
Note: Conditional mutant. Double labeled: red - Adgre1; green - reporter.
Structure Cell Type Level Pattern Image Note
TS28: aortic valve macrophage Present 3Q

Specimen 3U: postnatal day 28; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Nfatc1tm1.1(cre)Bz/Nfatc1+ (more )
Note: Conditional mutant. Double labeled: red - Adgre1; green - reporter.
Structure Cell Type Level Pattern Image Note
TS28: aortic valve macrophage Present 3U

Specimen 3Y: postnatal adult; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Nfatc1tm1.1(cre)Bz/Nfatc1+ (more )
Note: Conditional mutant. Double labeled: red - Adgre1; green - reporter.
Structure Cell Type Level Pattern Image Note
TS28: aortic valve macrophage Present 3Y

Specimen S1D: embryonic day 13.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Nfatc1tm1.1(cre)Bz/Nfatc1+ (more )
Note: Conditional mutant. Triple labeled: red - Adgre1; gray - Tnnt2 (assay MGI:8406223); green - reporter.
Structure Cell Type Level Pattern Image Note
TS21: endocardial cushion macrophage Present S1D

Specimen S1E: embryonic day 13.5; Gt(ROSA)26Sortm1(EYFP)Cos/Gt(ROSA)26Sor+, Nfatc1tm1.1(cre)Bz/Nfatc1+ (more )
Note: Conditional mutant. Triple labeled: red - Adgre1; gray - Tnnt2 (assay MGI:8406223); green - reporter.
Structure Cell Type Level Pattern Image Note
TS21: endocardial cushion macrophage Present S1E


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/06/2026
MGI 6.29
The Jackson Laboratory