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Gene Expression Data
Assay Details
Assay
Reference: J:348078 Nie X, et al., Piezo1 and Piezo2 collectively regulate jawbone development. Development. 2024 May 1;151(9):dev202386
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8289041
Gene symbol: Acta2
Gene name: actin alpha 2, smooth muscle, aorta
Antibody: Anti-smooth muscle alpha-Actin (clone 1A4)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 3M: embryonic day 16.5; Piezo1tm2.1Apat/Piezo1tm2.1Apat, Piezo2tm2.2Apat/Piezo2tm2.2Apat (more )
Structure Level Pattern Image Note
TS24: blood vessel smooth muscle Present 3M

Specimen 3N: embryonic day 16.5; E2f1Tg(Wnt1-cre)2Sor/E2f1+, Piezo1tm2.1Apat/Piezo1tm2.1Apat, Piezo2tm2.2Apat/Piezo2tm2.2Apat (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: blood vessel smooth muscle Present 3N The smooth muscle layers of the vasculatures were poorly formed in dCKO mice.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/14/2026
MGI 6.24
The Jackson Laboratory