Satb2 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:349721 Borisova E, et al., Protein translation rate determines neocortical neuron fate. Nat Commun. 2024 Jun 7;15(1):4879
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:8289038
Gene symbol:	Satb2
Gene name:	special AT-rich sequence binding protein 2

Antibody:	anti-SATB2
Assay notes:	Two antibodies were described, but the one used in this assay was not detailed. anti-Anti-SATB2 MGI:6159067 may have been used in this assay.

Results

Specimen S7a Satb2 E12.5BrdU-P2 CTR: postnatal day 2; Ern1^tm2.1Tiw/Ern1^tm2.1Tiw (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS27: cerebral cortex	cerebral cortex neuron	Present		S7a Satb2/CTIP2 E12.5BrdU-P2 CTR

Specimen S7a Satb2 E12.5BrdU-P2 cKO: postnatal day 2; Emx1^tm1(cre)Krj/Emx1⁺, Ern1^tm2.1Tiw/Ern1^tm2.1Tiw (more

)
Note: Conditional mutant.

Structure	Cell Type	Level	Pattern	Image	Note
TS27: cerebral cortex	cerebral cortex neuron	Present		S7a Satb2/CTIP2 E12.5BrdU-P2 cKO

Specimen S7a Satb2 E14.5BrdU-P2 CTR: postnatal day 2; Ern1^tm2.1Tiw/Ern1^tm2.1Tiw (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS27: cerebral cortex	cerebral cortex neuron	Present		S7a Satb2/CTIP2 E14.5BrdU-P2 CTR

Specimen S7a Satb2 E14.5BrdU-P2 cKO: postnatal day 2; Emx1^tm1(cre)Krj/Emx1⁺, Ern1^tm2.1Tiw/Ern1^tm2.1Tiw (more

)
Note: Conditional mutant.

Structure	Cell Type	Level	Pattern	Image	Note
TS27: cerebral cortex	cerebral cortex neuron	Present		S7a Satb2/CTIP2 E14.5BrdU-P2 cKO

Specimen S8a Satb2 Ire1a f/f: embryonic day 16.5; Ern1^tm2.1Tiw/Ern1^tm2.1Tiw (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS24: cerebral cortex	cerebral cortex neuron	Present		S8a Satb2 f/f

Specimen S8a Satb2 Emx1Cre/+;Ire1a f/f: embryonic day 16.5; Emx1^tm1(cre)Krj/Emx1⁺, Ern1^tm2.1Tiw/Ern1^tm2.1Tiw (more

)
Note: Conditional mutant.

Structure	Cell Type	Level	Pattern	Image	Note
TS24: cerebral cortex	cerebral cortex neuron	Present	Regionally restricted	S8a Satb2 Cre;f/f	Fewer Satb2-expressing neurons.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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