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Gene Expression Data
Assay Details
Assay
Reference: J:317760 Ochsenbein AM, et al., Regulation of lymphangiogenesis in the diaphragm by macrophages and VEGFR-3 signaling. Angiogenesis. 2016 Oct;19(4):513-24
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8278888
Gene symbol: Prox1
Gene name: prospero homeobox 1
Antibody: anti-Prox-1
Detection system: Secondary antibody coupled to Alexa Fluor
Assay notes: The authors did not specify which antibody was used; MGI:5587807 may have been used instead.
Results
Specimen 1B: postnatal day 7 (more )
Note: Double labeled: red - Prox1; green - Lyve1 (assay MGI:8278881).
Structure Level Pattern Image Note
TS28: diaphragm Present 1B , 1C Expression is in the submesothelial initial diaphragmatic lymphatic plexus.
TS28: lymphatic vessel Present 1B , 1C Expression is in the submesothelial initial diaphragmatic lymphatic plexus.
Specimen 1J: postnatal day 7 (more )
Note: Triple labeled: cyan - Prox1; red - Acta2 (assay MGI:8278891); green - Pecam1 (assay MGI:8278886).
Structure Level Pattern Image Note
TS28: lymphatic vessel Present 1J
Specimen 4B: postnatal day 7 (more )
Note: Triple labeled: red - Prox1; green - Lyve1 (assay MGI:8278881); cyan - Mrc1 (assay MGI:8278884).
Structure Cell Type Level Pattern Image Note
TS28: lymphatic vessel Present 4B , 4C
TS28: diaphragm macrophage Absent 4C
Specimen 4E: embryonic day 14.5 (more )
Note: Double labeled: cyan - Prox1; green - Cd68 (assay MGI:8278885).
Structure Level Pattern Image Note
TS22: lymphatic vessel endothelium Present Single cells 4E
Specimen S1I: postnatal day 7 (more )
Note: Double labeled: green - Prox1; red - Pecam1 (assay MGI:8278886).
Structure Level Pattern Image Note
TS28: lymphatic vessel endothelium Present S1I
Specimen S1J: postnatal day 7; Csf1rtm1Ers/Csf1rtm1Ers (more )
Note: Double labeled: green - Prox1; red - Pecam1 (assay MGI:8278886).
Structure Level Pattern Image Note
TS28: lymphatic vessel endothelium Present S1J In this mutant the number of lymphatic vessel branches and lymphatic valves in mesenteric lymphatic vessels is the same as in wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
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