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Gene Expression Data
Assay Details
Assay
Reference: J:361959 Zeng S, et al., Identification of Gallbladder-Specific Distal Regulatory Sequence of Murine Sox17. Genes Cells. 2025 Jan;30(1):e13186
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8276538
Gene symbol: Sox17
Gene name: SRY (sex determining region Y)-box 17
Antibody: anti-Sox17 (AF1924)
Detection system: Secondary antibody
Results
Specimen S2C WT: postnatal week 8 (more )
Structure Level Pattern Image Note
TS28: rete testis Present S2C WT , S2C WT inset
Specimen S2C dr.dr: postnatal week 8; Sox17em1Isct/Sox17em1Isct (more )
Structure Level Pattern Image Note
TS28: rete testis Present S2C Sox17dr/dr , S2C Sox17dr/dr inset Expression similar to wild type
Specimen S2D WT: postnatal week 3 (more )
Structure Level Pattern Image Note
TS28: uterus Present S2D WT
Specimen S2D dr/dr: postnatal week 3; Sox17em1Isct/Sox17em1Isct (more )
Structure Level Pattern Image Note
TS28: uterus Present S2D Sox17dr/dr Expression in luminal and glandular epithelium similar to wild type.
Specimen 3A Foregut WT: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum Absent 3A Foregut WT No expression in foregut.
Specimen 3A Foregut dr/dr: embryonic day 8.5; Sox17em1Isct/Sox17em1Isct (more )
Structure Level Pattern Image Note
TS13: foregut diverticulum Absent 3A Foregut Sox17dr/dr
Specimen 3A Midgut WT: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: midgut Present 3A Midgut WT
Specimen 3A Midgut dr/dr: embryonic day 8.5; Sox17em1Isct/Sox17em1Isct (more )
Structure Level Pattern Image Note
TS13: midgut Weak 3A Midgut Sox17dr/dr Expression weaker compared to wild type.
Specimen 3A Hindgut WT: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: hindgut diverticulum Present Regionally restricted 3A Hindgut WT Expression in hindgut dorsal regions,
Specimen 3A Hindgut dr/dr: embryonic day 8.5; Sox17em1Isct/Sox17em1Isct (more )
Structure Level Pattern Image Note
TS13: hindgut diverticulum Weak Regionally restricted 3A Hindgut Sox17dr/dr Expression weaker compared to wild type.
Specimen 3B WT: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: biliary bud Present 3B WT Primarily expressed in posterior foregut.
Specimen 3B +/-: embryonic day 9.5; Sox17tm1Sjm/Sox17+ (more )
Structure Level Pattern Image Note
TS15: biliary bud Weak 3B Sox17+/- Expression decreased to nearly 40% compared to wild type.
Specimen 3B dr/dr: embryonic day 9.5; Sox17em1Isct/Sox17em1Isct (more )
Structure Level Pattern Image Note
TS15: biliary bud Weak 3B Sox17dr/dr Expression weaker compared to wild type, but decrease less striking than in Sox17+/- embryos.
Specimen S3 Midgut WT: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: midgut Present S3_Midgut WT , S3_Midgut WT inset
Specimen S3 Midgut +/-: embryonic day 8.5; Sox17tm1Sjm/Sox17+ (more )
Structure Level Pattern Image Note
TS13: midgut Weak S3_Midgut Sox17+/- , S3_Midgut Sox17+/- inset Authors report 50% reduction in expression compared to wild type.
Specimen S3 Hindgut WT: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: hindgut diverticulum Present S3_Hindgut WT inset , S3_Hindgut WT
Specimen S3 Hindgut +/-: embryonic day 8.5; Sox17em1Isct/Sox17em1Isct (more )
Structure Level Pattern Image Note
TS13: hindgut diverticulum Weak S3_Hindgut Sox17+/- , S3_Hindgut Sox17+/- inset Authors report 50% reduction in expression compared to wild type.
Specimen 4A SOX17 WT: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: gallbladder Present 4A SOX17 WT inset , 4A SOX17 WT
Specimen 4A SOX17 +/-: embryonic day 13.5; Sox17tm1Sjm/Sox17+ (more )
Structure Level Pattern Image Note
TS21: gallbladder Weak 4A SOX17 Sox17+/- , 4A SOX17 Sox17+/- inset Expression decreased compared to wild type.
Specimen 4A SOX17 dr/dr: embryonic day 13.5; Sox17em1Isct/Sox17em1Isct (more )
Structure Level Pattern Image Note
TS21: gallbladder Weak 4A SOX17 Sox17dr/dr , 4A SOX17 Sox17dr/dr inset Expression decreased 50% compared to wild type.
Specimen 4B SOX17 WT: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: gallbladder epithelium Present 4B SOX17 WT inset , 4B SOX17 WT
Specimen 4B SOX17 +/-: postnatal day 0; Sox17tm1Sjm/Sox17+ (more )
Structure Level Pattern Image Note
TS27: gallbladder epithelium Weak 4B SOX17 Sox17+/- inset , 4B SOX17 Sox17+/- Expression decreased compared to wild type.
Specimen 4B SOX17 dr/dr: postnatal day 0; Sox17em1Isct/Sox17em1Isct (more )
Structure Level Pattern Image Note
TS27: gallbladder epithelium Weak 4B SOX17 Sox17dr/dr inset , 4B SOX17 Sox17dr/dr Expression decreased 50% compared to wild type, consistent with Sox17+/- embryos.
Specimen S4A WT: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: blood vessel Present S4A WT , S4A WT inset
Specimen S4A +/-: postnatal day 0; Sox17tm1Sjm/Sox17+ (more )
Structure Level Pattern Image Note
TS27: blood vessel Weak S4A Sox17+/- inset , S4A Sox17+/- Expression reduced compared to wild type.
Specimen S4A dr/dr: postnatal day 0; Sox17em1Isct/Sox17em1Isct (more )
Structure Level Pattern Image Note
TS27: blood vessel Present S4A Sox17dr/dr inset , S4A Sox17dr/dr Expression similar compared to wild type.
Specimen S4B Rete testes WT: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: rete testis Present S4B Rete testes WT , S4B Rete testes WT inset
Specimen S4B Rete testes +/-: postnatal day 0; Sox17tm1Sjm/Sox17+ (more )
Structure Level Pattern Image Note
TS27: rete testis Weak S4B Rete testes Sox17+/- , S4B Rete testes Sox17+/- inset Expression reduced compared to wild type.
Specimen S4B Rete testes dr/dr: postnatal day 0; Sox17em1Isct/Sox17em1Isct (more )
Structure Level Pattern Image Note
TS27: rete testis Present S4B Rete testes Sox17dr/dr , S4B Rete testes Sox17dr/dr inset Expression similar compared to wild type.
Specimen S4B Oviducts WT: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: oviduct Present S4B Oviducts WT
Specimen S4B Oviducts +/-: postnatal day 0; Sox17tm1Sjm/Sox17+ (more )
Structure Level Pattern Image Note
TS27: oviduct Weak S4B Oviducts Sox17+/- Expression reduced compared to wild type.
Specimen S4B Oviducts dr/dr: postnatal day 0; Sox17em1Isct/Sox17em1Isct (more )
Structure Level Pattern Image Note
TS27: oviduct Present S4B Oviducts Sox17dr/dr Expression similar compared to wild type.
Specimen S4B Uteri WT: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: uterus Present S4B Uteri WT
Specimen S4B Uteri +/-: postnatal day 0; Sox17tm1Sjm/Sox17+ (more )
Structure Level Pattern Image Note
TS27: uterus Weak S4B Uteri Sox17+/- Expression reduced compared to wild type.
Specimen S4B Uteri dr/dr: postnatal day 0; Sox17em1Isct/Sox17em1Isct (more )
Structure Level Pattern Image Note
TS27: uterus Present S4B Uteri Sox17dr/dr Expression similar compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
MGI 6.29 		The Jackson Laboratory