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Gene Expression Data
Assay Details
Assay
Reference: J:366215 Rudat C, et al., PPARG contributes to urothelial integrity in the murine ureter by activating the expression of Shh and superficial cell-specific genes. Development. 2025 Apr 15;152(8)
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8268805
Gene symbol: Upk1b
Gene name: uroplakin 1B
Antibody: anti-Upk1b (clone 1E1; WH0007348M2)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2D UPK1B control: postnatal day 40; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS28: superficial cell layer of ureter Strong 2D UPK1B control Expression strong in S cells.
TS28: intermediate cell layer of ureter Weak 2D UPK1B control Expression weak in I cells.
Specimen 2D UPK1B cKO: postnatal day 40; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: ureter Absent 2D UPK1B cKO
Specimen 3C UPK1B E14.5 control: embryonic day 14.5; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS22: ureter Absent 3C UPK1B E14.5 control
Specimen 3C UPK1B E14.5cKO: embryonic day 14.5; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: ureter Absent 3C UPK1B E14.5 cKO
Specimen 3C UPK1B E16.5 control: embryonic day 16.5; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS24: superficial cell layer of ureter Present 3C UPK1B E16.5 control Expression activated in luminal cells at E16.5.
Specimen 3C UPK1B 16.5 cKO: embryonic day 16.5; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: urothelium of ureter Absent 3C UPK1B E16.5 cKO
Specimen 3C UPK1B E18.5 control: embryonic day 18.5; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS26: superficial cell layer of ureter Strong 3C UPK1B E18.5 control Strong expression in S cells.
TS26: intermediate cell layer of ureter Weak 3C UPK1B E18.5 control Weaker expression in I cells.
Specimen 3C UPK1B E18.5 cKO: embryonic day 18.5; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: urothelium of ureter Absent 3C UPK1B E18.5 cKO
Specimen 3C UPK1B P7 control: postnatal day 7; Ppargtm2Rev/? (more )
Structure Level Pattern Image Note
TS28: superficial cell layer of ureter Strong 3C UPK1B P7 control Strong expression in S cells.
TS28: intermediate cell layer of ureter Weak 3C UPK1B P7 control Weaker expression in I cells.
Specimen 3C UPK1B P7 cKO: postnatal day 7; Ppargtm2Rev/Ppargtm2Rev, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: superficial cell layer of ureter Present Single cells 3C UPK1B P7 cKO Expression only in a few luminal cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
MGI 6.29 		The Jackson Laboratory