Gene Expression Data
Assay Details
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Assay
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Reference:
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J:373931
Welton JM, et al., Loss of CMTR1 leads to gastrulation failure and early embryonic lethality. Dev Biol. 2025 Dec;528:1-12
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:8262928
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Gene symbol:
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T
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Gene name:
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brachyury, T-box transcription factor T
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Probe:
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T cDNA4
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
3C Control:
embryonic day 7.5
(more  )
Note: Littermate control
Specimen
3C Control:
(close  )
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Genetic Background:
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C57BL/6NJ
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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Note:
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Littermate control
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Specimen
3C KO:
(close )
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Genetic Background:
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C57BL/6NJ-Cmtr1em1(IMPC)J/Mmjax
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Mutant Allele(s):
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Cmtr1em1(IMPC)J/Cmtr1em1(IMPC)J
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Age:
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embryonic day 7.5
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Sex:
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Not Specified
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Type:
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whole mount
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Fixation:
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4% Paraformaldehyde
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| Structure |
Level |
Pattern |
Image |
Note |
| TS11: embryo |
Present |
Regionally restricted |
3C Brachyury KO
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In mutants is expression is confined to a distinct portion of the proximal epiblast, presumably demarcating the posterior of the embryo. It is a relatively small patch of expression that does not expand distally.
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Analysis Tools
