About   Help   FAQ
T cDNA4 Probe Detail
Nucleotide
Probe/Clone
  • Name
    T cDNA4
  • Sequence Type
    cDNA
  • ID
    MGI:2449091
  • Region Covered
    clone spans from nucleotide 1760 to the 3' end of pme 75.
  • Parent Clone
  • Insert Size
    0.3 kb
Source
  • Species
    mouse, laboratory
  • Age
    embryonic day 8.5
Genes
T brachyury, T-box transcription factor T
Expression
  • Assay Results
    132
Sequences
References
J:21262 Wilkinson DG, et al., Expression pattern of the mouse T gene and its role in mesoderm formation [see comments]. Nature. 1990 Feb 15;343(6259):657-9
J:19211 Conlon FL, et al., A primary requirement for nodal in the formation and maintenance of the primitive streak in the mouse. Development. 1994 Jul;120(7):1919-28
J:35540 Bouillet P, et al., A new mouse member of the Wnt gene family, mWnt-8, is expressed during early embryogenesis and is ectopically induced by retinoic acid. Mech Dev. 1996 Aug;58(1-2):141-52
J:37194 Thomas P, et al., Anterior primitive endoderm may be responsible for patterning the anterior neural plate in the mouse embryo. Curr Biol. 1996 Nov 1;6(11):1487-96
J:45579 Thomas PQ, et al., Hex: a homeobox gene revealing peri-implantation asymmetry in the mouse embryo and an early transient marker of endothelial cell precursors. Development. 1998 Jan;125(1):85-94
J:53656 Perea-Gomez A, et al., HNF3beta and Lim1 interact in the visceral endoderm to regulate primitive streak formation and anterior-posterior polarity in the mouse embryo. Development. 1999 Oct;126(20):4499-511
J:57262 Song J, et al., The type II activin receptors are essential for egg cylinder growth, gastrulation, and rostral head development in mice. Dev Biol. 1999 Sep 1;213(1):157-69
J:58413 Wasiak S, et al., Retinoic acid affects left-right patterning. Dev Biol. 1999 Nov 15;215(2):332-42
J:67152 Perea-Gomez A, et al., Otx2 is required for visceral endoderm movement and for the restriction of posterior signals in the epiblast of the mouse embryo. Development. 2001 Mar;128(5):753-65
J:71998 Tremblay KD, et al., Mouse embryos lacking Smad1 signals display defects in extra-embryonic tissues and germ cell formation. Development. 2001 Sep;128(18):3609-21
J:75947 van den Akker E, et al., Cdx1 and Cdx2 have overlapping functions in anteroposterior patterning and posterior axis elongation. Development. 2002 May;129(9):2181-93
J:77516 Jiang P, et al., Targeted deletion of the MLC1f/3f downstream enhancer results in precocious MLC expression and mesoderm ablation. Dev Biol. 2002 Mar 15;243(2):281-93
J:79513 Hayashi K, et al., SMAD1 signaling is critical for initial commitment of germ cell lineage from mouse epiblast. Mech Dev. 2002 Oct;118(1-2):99
J:115836 Garrick D, et al., Loss of Atrx affects trophoblast development and the pattern of X-inactivation in extraembryonic tissues. PLoS Genet. 2006 Apr;2(4):e58
J:124356 Bondareva AA, et al., Effects of thioredoxin reductase-1 deletion on embryogenesis and transcriptome. Free Radic Biol Med. 2007 Sep 15;43(6):911-23
J:131814 Fukusumi Y, et al., Wtap is required for differentiation of endoderm and mesoderm in the mouse embryo. Dev Dyn. 2008 Mar;237(3):618-29
J:139570 Capellini TD, et al., Pbx1/Pbx2 govern axial skeletal development by controlling Polycomb and Hox in mesoderm and Pax1/Pax9 in sclerotome. Dev Biol. 2008 Sep 15;321(2):500-14
J:163739 Leung AW, et al., Loss of procollagen IIA from the anterior mesendoderm disrupts the development of mouse embryonic forebrain. Dev Dyn. 2010 Sep;239(9):2319-29
J:166847 Tonissoo T, et al., Nucleotide exchange factor RIC-8 is indispensable in mammalian early development. Dev Dyn. 2010 Dec;239(12):3404-15
J:186556 Trask MC, et al., Yin-Yang1 is required for epithelial-to-mesenchymal transition and regulation of Nodal signaling during mammalian gastrulation. Dev Biol. 2012 Aug 15;368(2):273-82
J:317900 Tamashiro DA, et al., Nkx1-2 is a transcriptional repressor and is essential for the activation of Brachyury in P19 mouse embryonal carcinoma cell. Differentiation. 2012 Jun;83(5):282-92
J:229383 Serth K, et al., Generation of an 870 kb deletion encompassing the Skt/Etl4 locus by combination of inter- and intra-chromosomal recombination. BMC Genet. 2015;16:143
J:236404 Minocha S, et al., Epiblast-specific loss of HCF-1 leads to failure in anterior-posterior axis specification. Dev Biol. 2016 Oct 1;418(1):75-88

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
05/07/2024
MGI 6.23
The Jackson Laboratory