Tagln Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:321503 Meuser M, et al., FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:8262910
Gene symbol:	Tagln
Gene name:	transgelin

Antibody:	anti-SM22 alpha (ab14106)
Detection system:	Biotinylated secondary antibody/[Strept]avidin coupled to Alexa Fluor 555

Results

Specimen 3B E12.5 control: embryonic day 12.5; Fgfr1^tm5.1Sor/?, Fgfr2^tm1Dor/? (more

)
Note: Cre-negative littermates were used as controls.

Structure	Level	Pattern	Image	Note
TS20: ureter	Ambiguous		3B control E12.5 TAGLN

Specimen 3B E12.5 Fgfr2cKO: embryonic day 12.5; Fgfr1^tm5.1Sor/Fgfr1⁺, Fgfr2^tm1Dor/Fgfr2^tm1Dor, Tg(Pax2-cre)10Shwl/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS20: ureter	Ambiguous		3B Fgfr2cKO E12.5 TAGLN

Specimen 3B E14.5 control: embryonic day 14.5; Fgfr1^tm5.1Sor/?, Fgfr2^tm1Dor/? (more

)
Note: Cre-negative littermates were used as controls.

Structure	Level	Pattern	Image	Note
TS22: ureter	Ambiguous		3B control E14.5 TAGLN

Specimen 3B E14.5 Fgfr2cKO: embryonic day 14.5; Fgfr1^tm5.1Sor/Fgfr1⁺, Fgfr2^tm1Dor/Fgfr2^tm1Dor, Tg(Pax2-cre)10Shwl/0 (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS22: ureter	Ambiguous		3B Fgfr2cKO E14.5 TAGLN

Specimen 3B E15.5 control: embryonic day 15.5; Fgfr1^tm5.1Sor/?, Fgfr2^tm1Dor/? (more

)
Note: Cre-negative littermates were used as controls.

Structure	Cell Type	Level	Pattern	Image	Note
TS23: ureteral smooth muscle layer	ureter smooth muscle cell	Present		3B control E15.5 TAGLN

Specimen 3B E15.5 Fgfr2cKO: embryonic day 15.5; Fgfr1^tm5.1Sor/Fgfr1⁺, Fgfr2^tm1Dor/Fgfr2^tm1Dor, Tg(Pax2-cre)10Shwl/0 (more

)
Note: Conditional mutant.

Structure	Cell Type	Level	Pattern	Image	Note
TS23: ureteral smooth muscle layer	ureter smooth muscle cell	Ambiguous		3B Fgfr2cKO E15.5 TAGLN

Specimen 3B E16.5 control: embryonic day 16.5; Fgfr1^tm5.1Sor/?, Fgfr2^tm1Dor/? (more

)
Note: Cre-negative littermates were used as controls.

Structure	Cell Type	Level	Pattern	Image	Note
TS24: ureteral smooth muscle layer	ureter smooth muscle cell	Present		3B control E16.5 TAGLN

Specimen 3B E16.5 Fgfr2cKO: embryonic day 16.5; Fgfr1^tm5.1Sor/Fgfr1⁺, Fgfr2^tm1Dor/Fgfr2^tm1Dor, Tg(Pax2-cre)10Shwl/0 (more

)
Note: Conditional mutant.

Structure	Cell Type	Level	Pattern	Image	Note
TS24: ureteral smooth muscle layer	ureter smooth muscle cell	Present		3B Fgfr2cKO E16.5 TAGLN	Expression was delayed by 1 day.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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