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Gene Expression Data
Assay Details
Assay
Reference: J:321503 Meuser M, et al., FGFR2 signaling enhances the SHH-BMP4 signaling axis in early ureter development. Development. 2022 Jan 1;149(1):dev200021
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8262797
Gene symbol: Tagln
Gene name: transgelin
Antibody: anti-SM22 alpha (ab14106)
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to Alexa Fluor 488
Results
Specimen 2C +/+;Fgfr1fl/+;Fgfr2fl/+: embryonic day 18.5; Fgfr1tm5.1Sor/Fgfr1+, Fgfr2tm1Dor/Fgfr2+ (more )
Structure Cell Type Level Pattern Image Note
TS26: ureteral smooth muscle layer ureter smooth muscle cell Present 2C +/+;Fgfr1fl/+;Fgfr2fl/+ TAGLN
Specimen 2C Pax2-cre/+;Fgfr1fl/+;Fgfr2fl/+: embryonic day 18.5; Fgfr1tm5.1Sor/Fgfr1+, Fgfr2tm1Dor/Fgfr2+, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: ureteral smooth muscle layer ureter smooth muscle cell Present 2C Pax2-cre/+;Fgfr1fl/+;Fgfr2fl/+ TAGLN
Specimen 2C Pax2-cre/+;Fgfr1fl/fl;Fgfr2fl/+: embryonic day 18.5; Fgfr1tm5.1Sor/Fgfr1tm5.1Sor, Fgfr2tm1Dor/Fgfr2+, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: ureteral smooth muscle layer ureter smooth muscle cell Present 2C Pax2-cre/+;Fgfr1fl/fl;Fgfr2fl/+ TAGLN
Specimen 2C Pax2-cre/+;Fgfr1fl/fl;Fgfr2fl/fl: embryonic day 18.5; Fgfr1tm5.1Sor/Fgfr1tm5.1Sor, Fgfr2tm1Dor/Fgfr2tm1Dor, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: ureteral smooth muscle layer ureter smooth muscle cell Present 2C Pax2-cre/+;Fgfr1fl/fl;Fgfr2fl/fl TAGLN
Specimen 2C Pax2-cre/+;Fgfr1fl/+;Fgfr2fl/fl left: embryonic day 18.5; Fgfr1tm5.1Sor/Fgfr1+, Fgfr2tm1Dor/Fgfr2tm1Dor, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS26: ureteral smooth muscle layer ureter smooth muscle cell Present 2C Pax2-cre/+;Fgfr1fl/+;Fgfr2fl/fl TAGLN left
Specimen 2C Pax2-cre/+;Fgfr1fl/+;Fgfr2fl/fl right: embryonic day 18.5; Fgfr1tm5.1Sor/Fgfr1+, Fgfr2tm1Dor/Fgfr2tm1Dor, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant. Undilated ureter.
Structure Cell Type Level Pattern Image Note
TS26: ureteral smooth muscle layer ureter smooth muscle cell Present 2C Pax2-cre/+;Fgfr1fl/+;Fgfr2fl/fl TAGLN right
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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10/06/2026
MGI 6.29 		The Jackson Laboratory