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Gene Expression Data
Assay Details
Assay
Reference: J:286649 Hall EG, et al., SPECC1L regulates palate development downstream of IRF6. Hum Mol Genet. 2020 Mar 27;29(5):845-858
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8260876
Gene symbol: Specc1l
Gene name: sperm antigen with calponin homology and coiled-coil domains 1-like
Antibody: anti-Specc1l
Detection system: Secondary antibody coupled to Alexa Fluor 594
Assay notes: There were 2 antibodies listed: MGI:5495297 and MGI:8260795; the one used in this assay was not specified.
Results
Specimen 4A: embryonic day 13.5 (more )
Note: Double labeled: red - Specc1l; green - Trp63 (assay MGI:8260877).
Structure Cell Type Level Pattern Image Note
TS21: primary palate mesenchyme Present Regionally restricted 4A , 4A' Expression was detected in the cranial neural crest derived palatal mesenchyme.
TS21: primary palate epithelium Present Regionally restricted 4A , 4A' Expression was detected in the Trp63-positive basal cells.
TS21: primary palate peridermal cell Present Regionally restricted 4A' , 4A Expression was detected in the Trp63-negative periderm cells.

Specimen 4B: embryonic day 14.0 (more )
Note: Double labeled: red - Specc1l; green - Trp63 (assay MGI:8260877).
Structure Cell Type Level Pattern Image Note
TS22: primary palate mesenchyme Present Regionally restricted 4B , 4B' Expression was detected in the cranial neural crest derived palatal mesenchyme.
TS22: primary palate epithelium Present Regionally restricted 4B' , 4B Expression was detected in the Trp63-positive basal cells.
TS22: primary palate peridermal cell Present Regionally restricted 4B , 4B' Expression was detected in the Trp63-negative periderm cells.

Specimen 4C: embryonic day 14.5 (more )
Note: Double labeled: red - Specc1l; green - Trp63 (assay MGI:8260877).
Structure Cell Type Level Pattern Image Note
TS22: primary palate mesenchyme Present Regionally restricted 4C , 4C' Expression was detected in the cranial neural crest derived palatal mesenchyme.
TS22: primary palate epithelium Present Regionally restricted 4C , 4C' Expression was detected in the Trp63-positive basal cells.
TS22: primary palate peridermal cell Present Regionally restricted 4C' , 4C Expression was detected in the Trp63-negative periderm cells.

Specimen 5A: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: primary palate Present Widespread 5A

Specimen 5B: embryonic day 15.5; Irf6Gt(OST398253)Lex/Irf6Gt(OST398253)Lex (more )
Structure Level Pattern Image Note
TS23: primary palate Absent 5B


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/08/2026
MGI 6.24
The Jackson Laboratory