Ins1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:307319 George NM, et al., Exploiting Expression of Hippo Effector, Yap, for Expansion of Functional Islet Mass. Mol Endocrinol. 2015 Nov;29(11):1594-607
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:8258979
Gene symbol:	Ins1
Gene name:	insulin I

Antibody:

Results

Specimen 1A Mst1^lox/lox/Mst2^lox/lox Mst1/2: postnatal; Stk3^tm1.1Rjo/Stk3^tm1.1Rjo, Stk4^tm1.1Rjo/Stk4^tm1.1Rjo (more

)
Note: Double labeled: green - Ins1 and Ins2; red - Stk3 (assay MGI:8258983).

Structure	Cell Type	Level	Pattern	Image	Note
TS28: islets of Langerhans	type B pancreatic cell	Present		1A Mst1^lox/lox/Mst2^lox/lox Mst1/2 bottom

Specimen 1A Mst1^lox/lox/Mst2^lox/lox Yap: postnatal; Stk3^tm1.1Rjo/Stk3^tm1.1Rjo, Stk4^tm1.1Rjo/Stk4^tm1.1Rjo (more

)
Note: Double labeled: green - Ins1 and Ins2; red - Yap1 (assay MGI:8258984).

Structure	Cell Type	Level	Pattern	Image	Note
TS28: islets of Langerhans	type B pancreatic cell	Present		1A Mst1^lox/lox/Mst2^lox/lox Yap bottom

Specimen 1A Ins-Cre/Mst1^lox/lox/Mst2^lox/lox Mst1/2: postnatal; Stk3^tm1.1Rjo/Stk3^tm1.1Rjo, Stk4^tm1.1Rjo/Stk4^tm1.1Rjo, Tg(Ins2-cre)25Mgn/0 (more

)
Note: Conditional mutant. Double labeled: green - Ins1 and Ins2; red - Stk3 (assay MGI:8258983).

Structure	Cell Type	Level	Pattern	Image	Note
TS28: islets of Langerhans	type B pancreatic cell	Present		1A Ins-Cre/Mst1^lox/lox/Mst2^lox/lox Mst1/2 bottom

Specimen 1A Ins-Cre/Mst1^lox/lox/Mst2^lox/lox Yap: postnatal; Stk3^tm1.1Rjo/Stk3^tm1.1Rjo, Stk4^tm1.1Rjo/Stk4^tm1.1Rjo, Tg(Ins2-cre)25Mgn/0 (more

)
Note: Conditional mutant. Double labeled: green - Ins1 and Ins2; red - Yap1 (assay MGI:8258984).

Structure	Cell Type	Level	Pattern	Image	Note
TS28: islets of Langerhans	type B pancreatic cell	Present		1A Ins-Cre/Mst1^lox/lox/Mst2^lox/lox Yap bottom

Specimen 1B top: postnatal day 2 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS27: islets of Langerhans	type B pancreatic cell	Present		1B Insulin top

Specimen 1B bottom: postnatal day 2 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS27: islets of Langerhans	type B pancreatic cell	Present		1B Insulin bottom

Specimen S1A: postnatal day 2 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS27: islets of Langerhans	type B pancreatic cell	Present		S1A Insulin

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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