Bhlhe22 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:372845 Napoli FR, et al., Microphthalmia and Disrupted Retinal Development Due to a LacZ Knock-in/Knock-Out Allele at the Vsx2 Locus. Eye Brain. 2024;16:115-131
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:8257030
Gene symbol:	Bhlhe22
Gene name:	basic helix-loop-helix family, member e22

Antibody:

anti-BHLHB5 (E-17; sc-6045)

Results

4D ©

Specimen 4D: embryonic day 12.5; Vsx2^{tm1b(EUCOMM)Wtsi}/Vsx2⁺ (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS20: retina	amacrine cell	Present		4D

4J ©

Specimen 4J: embryonic day 12.5; Vsx2^{tm1b(EUCOMM)Wtsi}/Vsx2^{tm1b(EUCOMM)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS20: retina	Absent		4J	No expression in central retina at E12.5

Specimen +/Z not shown: embryonic day 13.5; Vsx2^{tm1b(EUCOMM)Wtsi}/Vsx2⁺ (more

)

Structure	Level	Pattern	Image	Note
TS21: retina	Present

Specimen Z/Z not shown: embryonic day 13.5; Vsx2^{tm1b(EUCOMM)Wtsi}/Vsx2^{tm1b(EUCOMM)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS21: retina	Absent			Expression not detected in central retina at E13.5.

4P ©

Specimen 4P: embryonic day 15.5; Vsx2^{tm1b(EUCOMM)Wtsi}/Vsx2⁺ (more

)

Structure	Level	Pattern	Image	Note
TS23: retina	Present		4P

4V ©

Specimen 4V: embryonic day 15.5; Vsx2^{tm1b(EUCOMM)Wtsi}/Vsx2^{tm1b(EUCOMM)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS23: retina	Present	Regionally restricted	4V	Expression centrally restricted at E15.5

7K ©

Specimen 7K: postnatal day 0; Vsx2^{tm1b(EUCOMM)Wtsi}/Vsx2⁺ (more

)

Structure	Level	Pattern	Image	Note
TS27: retina	Present		7K

7L ©

Specimen 7L: postnatal day 0; Vsx2^{tm1b(EUCOMM)Wtsi}/Vsx2^{tm1b(EUCOMM)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS27: retina	Present	Regionally restricted	7L	Expressed in a disorganized manner.

8K ©

Specimen 8K: postnatal day 10; Vsx2^{tm1b(EUCOMM)Wtsi}/Vsx2⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: retina	Present		8K

8L ©

Specimen 8L: postnatal day 10; Vsx2^{tm1b(EUCOMM)Wtsi}/Vsx2^{tm1b(EUCOMM)Wtsi} (more

)

Structure	Level	Pattern	Image	Note
TS28: retina	Present	Regionally restricted	8L	Disorganized pattern of new neurons,.

9K ©

Specimen 9K: postnatal day 28; Vsx2^{tm1b(EUCOMM)Wtsi}/Vsx2⁺ (more

)

Structure	Level	Pattern	Image	Note
TS28: retina	Present		9K

9L ©

Specimen 9L: postnatal day 28; Vsx2^{tm1b(EUCOMM)Wtsi}/Vsx2^{tm1b(EUCOMM)Wtsi} (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS28: retina	amacrine cell	Present	Regionally restricted	9L	Aberrantly proliferating cells interspersed with progenitors, differentiating neuronal cells, Muller glia, retinal ganglion cells, amacrine cells and photoreceptors.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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