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Gene Expression Data
Assay Details
Assay
Reference: J:170604 Zhang Z, et al., The microRNA-processing enzyme Dicer is dispensable for somite segmentation but essential for limb bud positioning. Dev Biol. 2011 Mar 15;351(2):254-65
Assay type: RNA in situ
MGI Accession ID: MGI:8190644
Gene symbol: Lfng
Gene name: LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
Probe: Lfng probe
Assay notes: Tcre;Dicer or mutant samples could be either Tcre;Dicer<del/flox> or Tcre;Dicer<flox/flox>, which are phenotypically indistinguishable from one another. Tcre;Dicer<del/+> and Tcre;Dicer<flox/+> embryos are normal and used as controls.
Results
Specimen 2C: embryonic day 10.5; Dicer1tm1Bdh/Dicer1+, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant. Phase I Lfng expression oscillation.
Structure Level Pattern Image Note
TS17: unsegmented mesenchyme Present Regionally restricted 2C Expression was detected in the presomitic mesoderm in the phase I oscillation pattern.
Specimen 2D: embryonic day 10.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant. Phase I Lfng expression oscillation.
Structure Level Pattern Image Note
TS17: unsegmented mesenchyme Weak Regionally restricted 2D Expression was detected in the mutant presomitic mesoderm in the phase I oscillation pattern but was reduced in intensity compared to wild type.
Specimen 2E: embryonic day 10.5; Dicer1tm1Bdh/Dicer1+, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant. Phase II Lfng expression oscillation.
Structure Level Pattern Image Note
TS17: unsegmented mesenchyme Present Regionally restricted 2E Expression was detected in the presomitic mesoderm in the phase II oscillation pattern.
Specimen 2F: embryonic day 10.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant. Phase II Lfng expression oscillation.
Structure Level Pattern Image Note
TS17: unsegmented mesenchyme Weak Regionally restricted 2F Expression was detected in the mutant presomitic mesoderm in the phase II oscillation pattern but was reduced in intensity compared to wild type.
Specimen 2G: embryonic day 10.5; Dicer1tm1Bdh/Dicer1+, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant. Phase III Lfng expression oscillation.
Structure Level Pattern Image Note
TS17: unsegmented mesenchyme Present Regionally restricted 2G Expression was detected in the presomitic mesoderm in the phase III oscillation pattern.
Specimen 2H: embryonic day 10.5; Dicer1tm1Bdh/Dicer1tm1Bdh, Tg(T-cre)1Lwd/0 (more )
Note: Conditional mutant. Phase III Lfng expression oscillation.
Structure Level Pattern Image Note
TS17: unsegmented mesenchyme Weak Regionally restricted 2H Expression was detected in the mutant presomitic mesoderm in the phase III oscillation pattern but was reduced in intensity compared to wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory