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Gene Expression Data
Assay Details
Assay
Reference: J:181272 Le TT, et al., Requirements for Jag1-Rbpj mediated Notch signaling during early mouse lens development. Dev Dyn. 2012 Mar;241(3):493-504
Assay type: Immunohistochemistry
MGI Accession ID: MGI:8172426
Gene symbol: Prox1
Gene name: prospero homeobox 1
Antibody: anti-Prox1
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 5K: embryonic day 11.5; Gt(ROSA)26Sortm1(Notch1)Dam/Gt(ROSA)26Sortm1(Notch1)Dam (more )
Note: Double labeled: red - Prox1; green - Cdh1 (assay MGI:8172376).
Structure Level Pattern Image Note
TS19: lens vesicle Present Regionally restricted 5K Expressed in the posterior committed lens progenitor cells.

Specimen 6I: embryonic day 12.5; Rbpjtm1Hon/Rbpjtm1Hon (more )
Structure Cell Type Level Pattern Image Note
TS20: liver hepatocyte Present 6I

Specimen 6J: embryonic day 12.5; Rbpjtm1Hon/Rbpjtm1Hon, Tfap2atm1(cre)Moon/Tfap2a+ (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS20: liver hepatocyte Present 6J Abnormally small liver, but with a proportional distribution of Prox1+ hepatocytes.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory