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Gene Expression Data
Assay Details
Assay
Reference: J:178173 Mastracci TL, et al., Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression. Dev Biol. 2011 Nov 1;359(1):1-11
Assay type: RT-PCR
MGI Accession ID: MGI:8161697
Gene symbol: Sst
Gene name: somatostatin
Probe: Mm00436671_m1
Assay notes: Quantitative RT-PCR. Relative expression was normalized to Ppib.
Results
Image: 5B ©

 Sample Information Bands Other Sample Information
Lane AgeStructure Size Not Specified Amount Genetic BackgroundMutant Allele(s)Sex Note
WT E12.5 TS20: pancreas Ambiguous (a) Not Specified Not Specified Not Specified
Arx deltapanc E12.5 TS20: pancreas Present (b) Not Specified involves: 129/Sv * Black Swiss * FVB/N Arxtm1Gldn/?, Tg(Pdx1-cre)6Tuv/0Not Specified Conditional mutant. Arx<tm1Gldn>/Arx<tm1Gldn> in female, Arx<tm1Gldn>/Y in male.
Nkx2.2 null E12.5 TS20: pancreas Weak Not Specified involves: 129X1/SvJ * Black Swiss Nkx2-2tm1Jlr/Nkx2-2tm1JlrNot Specified
Nkx2.2 null;Arx deltapanc E12.5 TS20: pancreas Present (b) Not Specified involves: 129/Sv * 129X1/SvJ * Black Swiss * FVB/N Arxtm1Gldn/?, Nkx2-2tm1Jlr/Nkx2-2tm1Jlr, Tg(Pdx1-cre)6Tuv/0Not Specified Conditional mutant. Arx<tm1Gldn>/Arx<tm1Gldn> in female, Arx<tm1Gldn>/Y in male.
WT E15.5 TS23: pancreas Present Not Specified Not Specified Not Specified
Arx deltapanc E15.5 TS23: pancreas Present (c) Not Specified involves: 129/Sv * Black Swiss * FVB/N Arxtm1Gldn/?, Tg(Pdx1-cre)6Tuv/0Not Specified Conditional mutant. Arx<tm1Gldn>/Arx<tm1Gldn> in female, Arx<tm1Gldn>/Y in male.
Nkx2.2 null E15.5 TS23: pancreas Present (d) Not Specified involves: 129X1/SvJ * Black Swiss Nkx2-2tm1Jlr/Nkx2-2tm1JlrNot Specified
Nkx2.2 null;Arx deltapanc E15.5 TS23: pancreas Strong (e) Not Specified involves: 129/Sv * 129X1/SvJ * Black Swiss * FVB/N Arxtm1Gldn/?, Nkx2-2tm1Jlr/Nkx2-2tm1Jlr, Tg(Pdx1-cre)6Tuv/0Not Specified Conditional mutant. Arx<tm1Gldn>/Arx<tm1Gldn> in female, Arx<tm1Gldn>/Y in male.
Notes:
(a) Trace or absent.
(b) Significantly upregulated expression compared with the wild-type.
(c) Increased expression compared with the wild-type.
(d) No significant change compared with the wild-type.
(e) Significantly upregulated expression compared with the wild-type, higher than in the single Arx cKO.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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