Ppy Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:178173 Mastracci TL, et al., Nkx2.2 and Arx genetically interact to regulate pancreatic endocrine cell development and endocrine hormone expression. Dev Biol. 2011 Nov 1;359(1):1-11
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:8161674
Gene symbol:	Ppy
Gene name:	pancreatic polypeptide

Antibody:	anti-pancreatic polypeptide
Detection system:	Secondary antibody coupled to Cy3

Results

4I ©

Specimen 4I: postnatal day 0 (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS27: pancreas	pancreatic PP cell	Present		4I

4J ©

Specimen 4J: postnatal day 0; Arx^tm1Gldn/?, Tg(Pdx1-cre)6Tuv/0 (more

)
Note: Conditional mutant. Arx^tm1Gldn/Arx^tm1Gldn in female, Arx^tm1Gldn/Y in male.

Structure	Cell Type	Level	Pattern	Image	Note
TS27: pancreas	pancreatic PP cell	Present		4J	Similar as in the wild-type (quantified in Fig 4Q).

4K ©

Specimen 4K: postnatal day 0; Nkx2-2^tm1Jlr/Nkx2-2^tm1Jlr (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS27: pancreas	pancreatic PP cell	Present		4K	Reduced number of positive cells, compared with the wild-type (quantified in Fig 4Q).

4L ©

Specimen 4L: postnatal day 0; Arx^tm1Gldn/?, Nkx2-2^tm1Jlr/Nkx2-2^tm1Jlr, Tg(Pdx1-cre)6Tuv/0 (more

)
Note: Conditional mutant. Arx^tm1Gldn/Arx^tm1Gldn in female, Arx^tm1Gldn/Y in male.

Structure	Cell Type	Level	Pattern	Image	Note
TS27: pancreas	pancreatic PP cell	Present		4L	Restored back to similar as in the wild-type (quantified in Fig 4Q).

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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