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Gene Expression Data
Assay Details
Assay
Reference: J:124892 Flames N, et al., Delineation of multiple subpallial progenitor domains by the combinatorial expression of transcriptional codes. J Neurosci. 2007 Sep 5;27(36):9682-95
Assay type: RNA in situ
MGI Accession ID: MGI:7865771
Gene symbol: Nkx2-1
Gene name: NK2 homeobox 1
Probe: Nkx2.1 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2E/I: embryonic day 13.5 (more )
Note: rostral subpallium
Structure Level Pattern Image Note
TS21: lateral ganglionic eminence ventricular zone Absent 2E No expression in the progenitor ventricular regions.
TS21: medial ganglionic eminence Strong 2I , 2E
TS21: telencephalon Strong Regionally restricted 2E , 2I Expressed in the septum.

Specimen 3E: embryonic day 13.5 (more )
Note: rostral-intermediate subpallium
Structure Level Pattern Image Note
TS21: lateral ganglionic eminence Absent 3E
TS21: medial ganglionic eminence Strong 3E
TS21: preoptic area Strong 3E

Specimen 4G/K: embryonic day 13.5 (more )
Note: caudal-intermediate subpallium
Structure Level Pattern Image Note
TS21: medial ganglionic eminence ventricular zone Present Regionally restricted 4K , 4G Ventricular expression showed the presence of MGE progenitor domains at this caudal level (pMGE3).

Specimen 5E: embryonic day 13.5 (more )
Note: caudal subpallium
Structure Level Pattern Image Note
TS21: lateral ganglionic eminence Absent 5E

Specimen 6E: embryonic day 13.5 (more )
Note: subpallial septum
Structure Level Pattern Image Note
TS21: medial ganglionic eminence Strong 6E
TS21: lateral ganglionic eminence Absent 6E
TS21: telencephalon Present Regionally restricted 6E Expressed in the most ventromedial part of the septum (pSe4 to pSe6).

Specimen 9A: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: medial ganglionic eminence Strong 9A
TS21: preoptic area Strong 9A
TS21: telencephalon Strong Regionally restricted 9A Expressed in the septum.
TS21: lateral ganglionic eminence Absent 9A
TS21: caudal ganglionic eminence Present Regionally restricted 9A Expressed in part of the caudal ganglionic eminence.

Specimen S1C: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: telencephalon Strong Regionally restricted S1C No expression in the lateral ganglionic eminence. Expressed in medial ganglionic eminence (pMGE1-5).


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/06/2026
MGI 6.29
The Jackson Laboratory