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Gene Expression Data
Assay Details
Assay
Reference: J:306379 Mohad V, et al., Inactivation of Lats1 and Lats2 highlights the role of hippo pathway effector YAP in larynx and vocal fold epithelium morphogenesis. Dev Biol. 2021 May;473:33-49
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7861501
Gene symbol: Lama5
Gene name: laminin, alpha 5
Antibody: anti-Laminin 5 (ab11575)
Detection system: Secondary antibody coupled to Cy3
Results
Specimen 10C: postnatal day 0; Lats1tm1.1Jfm/Lats1+, Lats2tm1.1Jfm/Lats2+, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: vocal folds Strong Regionally restricted 10C Strong expression in fully developed and intact basement membrane under layered epithelial cells.
Specimen 10D: postnatal day 0; Lats1tm1.1Jfm/Lats1tm1.2Jfm, Lats2tm1.1Jfm/Lats2tm1.2Jfm, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: vocal folds Present Patchy 10D Fragmented expression throughout disrupted epithelium.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory