Casp3 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:306379 Mohad V, et al., Inactivation of Lats1 and Lats2 highlights the role of hippo pathway effector YAP in larynx and vocal fold epithelium morphogenesis. Dev Biol. 2021 May;473:33-49
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7861499
Gene symbol:	Casp3
Gene name:	caspase 3

Antibody:	anti-cleaved caspase-3 (Asp175) (5A1E) (#9664)
Detection system:	Secondary antibody coupled to Cy3

Results

9A ©

Specimen 9A: postnatal day 0; Lats1^tm1.1Jfm/Lats1⁺, Lats2^tm1.1Jfm/Lats2⁺, Shh^{tm1(EGFP/cre)Cjt}/Shh⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS27: vocal folds	Present		9A

9B ©

Specimen 9B: postnatal day 0; Lats1^tm1.1Jfm/Lats1^tm1.2Jfm, Lats2^tm1.1Jfm/Lats2^tm1.2Jfm, Shh^{tm1(EGFP/cre)Cjt}/Shh⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS27: vocal folds	Absent		9B	Authors report a loss of apototic cells in epithelium compared to littermate controls.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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