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Gene Expression Data
Assay Details
Assay
Reference: J:243177 Lania G, et al., TBX1 Represses Vegfr2 Gene Expression and Enhances the Cardiac Fate of VEGFR2+ Cells. PLoS One. 2015;10(9):e0138525
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7859263
Gene symbol: Kdr
Gene name: kinase insert domain protein receptor
Antibody: anti-CD309 (VEGFR2)
Detection system: Secondary antibody coupled to horseradish peroxidase
Results
Specimen 6B: embryonic day 9.5 (more )
Note: 23 somite stage embryo.
Structure Level Pattern Image Note
TS15: secondary heart field Present Regionally restricted 6B Expression is in the in the mesodermal/epithelial-like tissue of the posterior second heart field in the proximity of the cardiac inflow tract and in the dorsal mesenchyme protrusion region.
TS15: blood vessel Present Regionally restricted 6B Expression is in the endothelium.
Specimen 6B': embryonic day 9.5; Tbx1tm1Bld/Tbx1tm1Bld (more )
Note: 23 somite stage embryo.
Structure Level Pattern Image Note
TS15: secondary heart field Present Regionally restricted 6B' The expression domains in this mutant had expanded more dorsally and anteriorly compared to wild-type.
Specimen 6C: embryonic day 9.0 (more )
Note: 16 somite stage embryo.
Structure Level Pattern Image Note
TS14: secondary heart field Present 6C
Specimen 6C': embryonic day 9.0; Tbx1tm1Bld/Tbx1tm1Bld (more )
Note: 16 somite stage embryo.
Structure Level Pattern Image Note
TS14: secondary heart field Present 6C' The expression domain was asymmetric compared to wild-type.
Specimen 7E: embryonic day 8.5 (more )
Note: 8 somite stage embryo.
Structure Level Pattern Image Note
TS13: branchial arch mesenchyme derived from head mesoderm Present 7E
Specimen 7F: embryonic day 8.5 (more )
Note: 8 somite stage embryo.
Structure Level Pattern Image Note
TS13: branchial arch mesenchyme derived from head mesoderm Present 7F
Specimen 7G: embryonic day 8.5; Tbx1tm1Bld/Tbx1tm1Bld (more )
Note: 8 somite stage embryo.
Structure Level Pattern Image Note
TS13: branchial arch mesenchyme derived from head mesoderm Present 7G The expression domain had expanded in this mutant compared to wild-type.
Specimen 7H: embryonic day 8.5; Tbx1tm1Bld/Tbx1tm1Bld (more )
Note: 8 somite stage embryo.
Structure Level Pattern Image Note
TS13: branchial arch mesenchyme derived from head mesoderm Present 7H The expression domain had expanded in this mutant compared to wild-type.
Specimen S5 16s +/+ rostral: embryonic day 9.0 (more )
Note: 16 somite stage embryo.
Structure Level Pattern Image Note
TS14: 1st branchial arch Present S5_16s +/+ rostral
Specimen S5 16s +/+ medial: embryonic day 9.0 (more )
Note: 16 somite stage embryo.
Structure Level Pattern Image Note
TS14: 1st branchial arch Present S5_16s +/+ medial
Specimen S5 16s +/+ caudal: embryonic day 9.0 (more )
Note: 16 somite stage embryo.
Structure Level Pattern Image Note
TS14: 1st branchial arch Present S5_16s +/+ caudal
Specimen S5 16s -/- rostral: embryonic day 9.0; Tbx1tm1Bld/Tbx1tm1Bld (more )
Note: 16 somite stage embryo.
Structure Level Pattern Image Note
TS14: 1st branchial arch Present S5_16s -/- rostral In this mutant the expression domain had expanded compared to wild-type.
Specimen S5 16s -/- medial: embryonic day 9.0; Tbx1tm1Bld/Tbx1tm1Bld (more )
Note: 16 somite stage embryo.
Structure Level Pattern Image Note
TS14: 1st branchial arch Present S5_16s -/- medial In this mutant the expression domain had expanded compared to wild-type.
Specimen S5 16s -/- caudal: embryonic day 9.0; Tbx1tm1Bld/Tbx1tm1Bld (more )
Note: 16 somite stage embryo.
Structure Level Pattern Image Note
TS14: 1st branchial arch Present S5_16s -/- caudal In this mutant the expression domain had expanded compared to wild-type.
Specimen S5 20s +/+ rostral: embryonic day 9.0 (more )
Note: 20 somite stage embryo.
Structure Level Pattern Image Note
TS14: 1st branchial arch Present S5_20s +/+ rostral
Specimen S5 20s +/+ medial: embryonic day 9.0 (more )
Note: 20 somite stage embryo.
Structure Level Pattern Image Note
TS14: 1st branchial arch Present S5_20s +/+ medial
Specimen S5 20s +/+ caudal: embryonic day 9.0 (more )
Note: 20 somite stage embryo.
Structure Level Pattern Image Note
TS14: 1st branchial arch Present S5_20s +/+ caudal
Specimen S5 20s -/- rostral: embryonic day 9.0; Tbx1tm1Bld/Tbx1tm1Bld (more )
Note: 20 somite stage embryo.
Structure Level Pattern Image Note
TS14: 1st branchial arch Present S5_20s -/- rostral In this mutant the expression domain had expanded compared to wild-type.
Specimen S5 20s -/- medial: embryonic day 9.0; Tbx1tm1Bld/Tbx1tm1Bld (more )
Note: 20 somite stage embryo.
Structure Level Pattern Image Note
TS14: 1st branchial arch Present S5_20s -/- medial In this mutant the expression domain had expanded compared to wild-type.
Specimen S5 20s -/- caudal: embryonic day 9.0; Tbx1tm1Bld/Tbx1tm1Bld (more )
Note: 20 somite stage embryo.
Structure Level Pattern Image Note
TS14: 1st branchial arch Present S5_20s -/- caudal In this mutant the expression domain had expanded compared to wild-type.
Specimen S5 25s +/+ rostral: embryonic day 9.5 (more )
Note: 25 somite stage embryo.
Structure Level Pattern Image Note
TS15: 1st branchial arch Present S5_25s +/+ rostral
Specimen S5 25s +/+ medial: embryonic day 9.5 (more )
Note: 25 somite stage embryo.
Structure Level Pattern Image Note
TS15: 1st branchial arch Present S5_25s +/+ medial
Specimen S5 25s +/+ caudal: embryonic day 9.5 (more )
Note: 25 somite stage embryo.
Structure Level Pattern Image Note
TS15: 1st branchial arch Present S5_25s +/+ caudal
Specimen S5 25s -/- rostral: embryonic day 9.5; Tbx1tm1Bld/Tbx1tm1Bld (more )
Note: 25 somite stage embryo.
Structure Level Pattern Image Note
TS15: 1st branchial arch Present S5_25s -/- rostral In this mutant the expression domain had expanded compared to wild-type.
Specimen S5 25s -/- medial: embryonic day 9.5; Tbx1tm1Bld/Tbx1tm1Bld (more )
Note: 25 somite stage embryo.
Structure Level Pattern Image Note
TS15: 1st branchial arch Present S5_25s -/- medial In this mutant the expression domain had expanded compared to wild-type.
Specimen S5 25s -/- caudal: embryonic day 9.5; Tbx1tm1Bld/Tbx1tm1Bld (more )
Note: 25 somite stage embryo.
Structure Level Pattern Image Note
TS15: 1st branchial arch Present S5_25s -/- caudal In this mutant the expression domain had expanded compared to wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory