Gene Expression Data
Assay Details
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Assay
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Reference:
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J:149465
Holmes G, et al., Early onset of craniosynostosis in an Apert mouse model reveals critical features of this pathology. Dev Biol. 2009 Apr 15;328(2):273-84
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:7856729
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Gene symbol:
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Fgfr2
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Gene name:
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fibroblast growth factor receptor 2
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Results
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Specimen
2A WT:
embryonic day 13.5
(more  )
Specimen
2A WT:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: chondrocranium |
Present |
Regionally restricted |
2A WT Fgfr2
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Expression is in the frontal and parietal domains of the coronal suture.
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Specimen
2A AP:
embryonic day 13.5; Fgfr2tm1Ewj/Fgfr2 +
(more )
Specimen
2A AP:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Fgfr2tm1Ewj/Fgfr2+
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Age:
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embryonic day 13.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS21: chondrocranium |
Present |
Regionally restricted |
2A AP Fgfr2
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Expression in the basal suture starts to become continuous between the frontal and parietal domains.
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Specimen
3A:
embryonic day 15.5
(more )
Specimen
3A:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
3B top:
embryonic day 15.5; Fgfr2tm1Ewj/Fgfr2 +
(more )
Specimen
3B top:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Fgfr2tm1Ewj/Fgfr2+
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
3B 2nd:
embryonic day 15.5; Fgfr2tm1Ewj/Fgfr2 +
(more )
Specimen
3B 2nd:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Fgfr2tm1Ewj/Fgfr2+
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
3B 3rd:
embryonic day 15.5; Fgfr2tm1Ewj/Fgfr2 +
(more )
Specimen
3B 3rd:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Fgfr2tm1Ewj/Fgfr2+
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
3B 4th:
embryonic day 15.5; Fgfr2tm1Ewj/Fgfr2 +
(more )
Specimen
3B 4th:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Fgfr2tm1Ewj/Fgfr2+
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
3B 5th:
embryonic day 15.5; Fgfr2tm1Ewj/Fgfr2 +
(more )
Specimen
3B 5th:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Fgfr2tm1Ewj/Fgfr2+
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
not shown WT E12.5:
embryonic day 12.5
(more )
Specimen
not shown WT E12.5:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS20: chondrocranium |
osteoblast |
Present |
Regionally restricted |
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Expression is in the frontal and parietal domains of the coronal suture in osteoblasts at the osteogenic front and along the developing bone surfaces.
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Specimen
not shown AP E12.5:
embryonic day 12.5; Fgfr2tm1Ewj/Fgfr2 +
(more )
Specimen
not shown AP E12.5:
(close )
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Genetic Background:
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involves: 129S1/Sv * 129X1/SvJ
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Mutant Allele(s):
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Fgfr2tm1Ewj/Fgfr2+
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS20: chondrocranium |
osteoblast |
Present |
Regionally restricted |
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Expression in this mutant is the same as in wild-type.
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Analysis Tools