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Gene Expression Data
Assay Details
Assay
Reference: J:238086 Kusano R, et al., Targeted disruption of the mouse protein phosphatase ppm1l gene leads to structural abnormalities in the brain. FEBS Lett. 2016 Oct;590(20):3606-3615
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7840303
Gene symbol: Ppm1l
Gene name: protein phosphatase 1 (formerly 2C)-like
Reporter: lacZ
Direct Detection
Results
Specimen 1D E9.5: embryonic day 9.5; Ppm1ltm1Tkoba/Ppm1l+ (more )
Structure Level Pattern Image Note
TS15: future hindbrain Strong 1D E9.5
TS15: future midbrain Strong 1D E9.5
TS15: future spinal cord Strong 1D E9.5
TS15: future forebrain Strong Non-Uniform 1D E9.5 Expression is strong in the caudal prosencephalon and weak rostrally.
Specimen 1D E10.5: embryonic day 10.5; Ppm1ltm1Tkoba/Ppm1l+ (more )
Structure Level Pattern Image Note
TS17: future spinal cord Strong 1D E10.5
TS17: hindbrain Strong 1D E10.5
TS17: midbrain Strong 1D E10.5
TS17: forebrain Strong Non-Uniform 1D E10.5 Expression is strong in the caudal prosencephalon and weak rostrally.
Specimen 1D E11.5: embryonic day 11.5; Ppm1ltm1Tkoba/Ppm1l+ (more )
Structure Level Pattern Image Note
TS19: diencephalon Strong 1D E11.5
TS19: future spinal cord Strong 1D E11.5
TS19: hindbrain Strong 1D E11.5
TS19: midbrain Strong 1D E11.5
TS19: telencephalon Strong 1D E11.5
Specimen 1E: embryonic day 11.5; Ppm1ltm1Tkoba/Ppm1l+ (more )
Structure Level Pattern Image Note
TS19: telencephalon marginal layer Present 1E
TS19: telencephalon ventricular layer Absent 1E
Specimen 1F: embryonic day 11.5; Ppm1ltm1Tkoba/Ppm1l+ (more )
Structure Level Pattern Image Note
TS19: dorsal root ganglion Present 1F
TS19: neural tube marginal layer Present 1F
TS19: future spinal cord Present Regionally restricted 1F Expression is in the ventral horn.
TS19: neural tube ventricular layer Absent 1F
Specimen 1G: embryonic day 11.5; Ppm1ltm1Tkoba/Ppm1l+ (more )
Structure Level Pattern Image Note
TS19: neural retina Present Regionally restricted 1G Expression is in the inner surface.
Specimen 1H: embryonic day 11.5; Ppm1ltm1Tkoba/Ppm1l+ (more )
Structure Level Pattern Image Note
TS19: endocardial lining Present 1H
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory