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Gene Expression Data
Assay Details
Assay
Reference: J:353600 Liu X, et al., Dynamic regulation of alternative polyadenylation by PQBP1 during neurogenesis. Cell Rep. 2024 Aug 27;43(8):114525
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7797937
Gene symbol: Tbr1
Gene name: T-box brain transcription factor 1
Antibody: anti-Tbr1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen S6H Control: postnatal newborn (more )
Note: Double labeled: green - Tbr1; red - Bcl11b (assay MGI:7797935).
Structure Level Pattern Image Note
TS27: cerebral cortex Present Regionally restricted S6H Control Expression was layer-specific in the cortex.
Specimen S6H Pqbp1W215X: postnatal newborn; Pqbp1em1Jhhan/Pqbp1em1Jhhan (more )
Note: Double labeled: green - Tbr1; red - Bcl11b (assay MGI:7797935).
Structure Level Pattern Image Note
TS27: cerebral cortex Present Regionally restricted S6H Pqbp1W215X Expression of the layer-specific marker revealed a normal lamination pattern but a notable decrease in cortical thickness in Pqbp1<W215X> mice compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory