About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:355260 Moorwood K, et al., Grb7, Grb10 and Grb14, encoding the growth factor receptor-bound 7 family of signalling adaptor proteins have overlapping functions in the regulation of fetal growth and post-natal glucose metabolism. BMC Biol. 2024 Sep 30;22(1):221
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7797847
Gene symbol: Grb7
Gene name: growth factor receptor bound protein 7
Antibody: anti-Grb7 (N-20) sc-607
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 1A: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: dermis Present 1A
TS22: gut Present 1A
TS22: inner ear Present 1A
TS22: liver Present 1A
TS22: lung Present 1A
TS22: nasal epithelium Present 1A
TS22: pancreas Present 1A
TS22: pituitary gland Present 1A
TS22: rib cartilage condensation Present 1A
TS22: salivary gland Present 1A
TS22: stomach epithelium Present 1A
TS22: tooth Present 1A
TS22: cardiac muscle tissue Absent 1A
TS22: diaphragm Absent 1A
TS22: gut muscularis Absent 1A
TS22: skeletal muscle Absent 1A

Specimen 1B: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: submandibular gland primordium Present 1B
TS22: tooth Present 1B

Specimen 1C: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: renal tubule Present 1C
TS22: adrenal cortex Weak 1C

Specimen 1D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: bronchus Present 1D
TS22: liver Present 1D
TS22: pericardium Weak 1D
TS22: rib cartilage condensation Weak Regionally restricted 1D Expression is in ossified cartilage.
TS22: heart Absent 1D

Specimen 1E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: hindgut epithelium Present 1E
TS22: midgut epithelium Present 1E
TS22: pancreas Present Regionally restricted 1E Expression is in the endocrine component.

Specimen 1F: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: pancreas Very strong Regionally restricted 1F Expression is in the endocrine pancreas.

Specimen 3A: postnatal day 21 (more )
Structure Cell Type Level Pattern Image Note
TS28: islets of Langerhans pancreatic endocrine cell Present 3A

Specimen Table 1: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: inner ear epithelium Strong
TS22: liver Strong
TS22: lung epithelium Strong
TS22: metanephros epithelium Strong
TS22: nasal epithelium Strong
TS22: pituitary gland Strong
TS22: stomach epithelium Strong
TS22: submandibular gland primordium epithelium Strong
TS22: pancreas Strong Regionally restricted Expression is in the endocrine pancreas.
TS22: gut epithelium Strong Regionally restricted Expression is in the lower gut.
TS22: tooth Present
TS22: adrenal cortex Weak
TS22: pericardium Weak
TS22: cartilage Trace Regionally restricted Expression is in ossified cartilage.
TS22: central nervous system Present Regionally restricted Expression is in the pituitary gland and is absent in the rest of the central nervous system.
TS22: epidermis Absent
TS22: hindbrain Absent
TS22: midbrain Absent
TS22: skeletal muscle Absent
TS22: spinal cord Absent
TS22: telencephalon Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory