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Gene Expression Data
Assay Details
Assay
Reference: J:174488 Britz O, et al., A role for proneural genes in the maturation of cortical progenitor cells. Cereb Cortex. 2006 Jul;16 Suppl 1:i138-51
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7790494
Gene symbol: Neurog2
Gene name: neurogenin 2
Antibody: Anti-Ngn2
Detection system: Secondary antibody
Results
Specimen 1C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Present Scattered 1C Expressed in a small fraction (10%) of randomly distributed cortical nuclei.
Specimen 1F: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Present Regionally restricted 1F Expressed in the central region and were less abundant near the ventricular surface and at the ventricular zone/subventricular zone border.
Specimen 1L: embryonic day 12.5 (more )
Note: Double labeled: red - Neurog2; green - Ascl1 (assay MGI:7790492).
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Present 1L Many positive nuclei expressed Ascl1 (55.7%).
Specimen 1M: embryonic day 15.5 (more )
Note: Double labeled: red - Neurog2; green - Ascl1 (assay MGI:7790492).
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Present Regionally restricted 1M Nonoverlapping expression domains with Ascl1. The level of coexpression (11.4%) dropped substantially at E15.5 as compared with E12.5.
TS23: cerebral cortex subventricular zone Present 1M The level of coexpression (23.8%) remained slightly higher.
Specimen 1N: embryonic day 15.5 (more )
Note: Double labeled: red - Neurog2; green - Ascl1 (assay MGI:7790492).
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Present Regionally restricted 1N Nonoverlapping expression domains with Ascl1. The level of coexpression (11.4%) dropped substantially at E15.5 as compared with E12.5.
TS23: cerebral cortex subventricular zone Present 1N The level of coexpression (23.8%) remained slightly higher.
Specimen 1O: embryonic day 15.5 (more )
Note: Double labeled: red - Neurog2; green - Ascl1 (assay MGI:7790492).
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Present Regionally restricted 1O Nonoverlapping expression domains with Ascl1. The level of coexpression (11.4%) dropped substantially at E15.5 as compared with E12.5.
TS23: cerebral cortex subventricular zone Present 1O The level of coexpression (23.8%) remained slightly higher.
Specimen 2M/N: embryonic day 15.5 (more )
Note: Double labeled: red - Neurog2 protein; green - Neurog2 reporter (assay MGI:7790520).
Structure Level Pattern Image Note
TS23: cerebral cortex ventricular layer Present 2M , 2N GFP was largely coexpressed with Neurog2.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory