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Gene Expression Data
Assay Details
Assay
Reference: J:174095 Cai Z, et al., Loss of shp2-mediated mitogen-activated protein kinase signaling in muller glial cells results in retinal degeneration. Mol Cell Biol. 2011 Jul;31(14):2973-83
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7788464
Gene symbol: Calb1
Gene name: calbindin 1
Results
Specimen 2D WT: postnatal day 21 (more )
Structure Cell Type Level Pattern Image Note
TS28: retina layer retina horizontal cell Present 2D WT
Specimen 2D cKO: postnatal day 21; Ptpn11tm1Gsf/Ptpn11tm1Gsf, Tg(Six3-cre)69Frty/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: retina layer retina horizontal cell Present 2D cKO A 50% reduction was seen.
Specimen S3G: postnatal day 7 (more )
Structure Cell Type Level Pattern Image Note
TS28: retina layer retina horizontal cell Present S3G
Specimen S3H: postnatal day 7; Ptpn11tm1Gsf/Ptpn11tm1Gsf, Tg(Six3-cre)69Frty/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: retina layer retina horizontal cell Present S3H Similar as in the wild-type.
Specimen not shown: postnatal day 21; Krastm4Tyj/Krastm4Tyj, Ptpn11tm1Gsf/Ptpn11tm1Gsf, Tg(Six3-cre)69Frty/0 (more )
Note: Conditional mutant. Quantified in Fig 6T.
Structure Cell Type Level Pattern Image Note
TS28: retina layer retina horizontal cell Present Expression was restored to the wild-type level.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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07/08/2026
MGI 6.24 		The Jackson Laboratory