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Gene Expression Data
Assay Details
Assay
Reference: J:173619 Barron F, et al., Downregulation of Dlx5 and Dlx6 expression by Hand2 is essential for initiation of tongue morphogenesis. Development. 2011 Jun;138(11):2249-59
Assay type: RNA in situ
MGI Accession ID: MGI:7782468
Gene symbol: Dlx5
Gene name: distal-less homeobox 5
Probe: Dlx5 probe
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 6A: embryonic day 9.5; Hand2tm1.1Majh/Hand2tm1.1Majh (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch Present Widespread 6A
TS15: 2nd branchial arch Present 6A
Specimen 6B: embryonic day 9.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Hand2tm1.1Majh/Hand2tm1.1Majh (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: 1st branchial arch Present Widespread 6B
TS15: 2nd branchial arch Present 6B
Specimen 6K: embryonic day 10.5; Hand2tm1.1Majh/Hand2tm1.1Majh (more )
Note: ventral view
Structure Level Pattern Image Note
TS17: 1st branchial arch Present Regionally restricted 6K Expression was downregulated in the distal and oral aspects.
TS17: 2nd branchial arch Present 6K
Specimen 6K': embryonic day 10.5; Hand2tm1.1Majh/Hand2tm1.1Majh (more )
Note: oral view
Structure Level Pattern Image Note
TS17: 1st branchial arch Present Regionally restricted 6K' Expression was downregulated in the distal and oral aspects.
Specimen 6L: embryonic day 10.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Hand2tm1.1Majh/Hand2tm1.1Majh (more )
Note: Conditional mutant. ventral view
Structure Level Pattern Image Note
TS17: 1st branchial arch Present Widespread 6L Expression was present throughout the mandibular arch.
TS17: 2nd branchial arch Present 6L
Specimen 6L': embryonic day 10.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Hand2tm1.1Majh/Hand2tm1.1Majh (more )
Note: Conditional mutant. oral view
Structure Level Pattern Image Note
TS17: 1st branchial arch Present Widespread 6L' Expression was present throughout the mandibular arch.
Specimen 6M: embryonic day 11.5; Hand2tm1.1Majh/Hand2tm1.1Majh (more )
Structure Level Pattern Image Note
TS19: 1st branchial arch Present Regionally restricted 6M Expression was downregulated in the distal and oral aspects corresponding to the lateral lingual swelling.
Specimen 6N: embryonic day 11.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Hand2tm1.1Majh/Hand2tm1.1Majh (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: 1st branchial arch Present Widespread 6N Expression continued in the disto-oral region.
Specimen 6O: embryonic day 12.5; Hand2tm1.1Majh/Hand2tm1.1Majh (more )
Structure Level Pattern Image Note
TS20: tongue Present 6O
TS20: jaw Present Regionally restricted 6O Expressed in the proximal jaw.
Specimen 6P: embryonic day 12.5; H2az2Tg(Wnt1-cre)11Rth/H2az2+, Hand2tm1.1Majh/Hand2tm1.1Majh (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: jaw Present Regionally restricted 6P Expressed only in the proximal jaw, owing to the absence of the tongue.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory