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Gene Expression Data
Assay Details
Assay
Reference: J:238344 Koledova Z, et al., SPRY1 regulates mammary epithelial morphogenesis by modulating EGFR-dependent stromal paracrine signaling and ECM remodeling. Proc Natl Acad Sci U S A. 2016 Sep 27;113(39):E5731-40
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7778350
Gene symbol: Spry1
Gene name: sprouty RTK signaling antagonist 1
Reporter: lacZ
Direct Detection
Results
Specimen 1D: embryonic day 12.5; Spry1tm2Jdli/Spry1+ (more )
Structure Level Pattern Image Note
TS20: mammary bud Present 1D' , 1D
Specimen 1E: embryonic day 12.5; Spry1tm2Jdli/Spry1+ (more )
Structure Level Pattern Image Note
TS20: mammary bud Present 1E
Specimen 1F: postnatal week 5; Spry1tm2Jdli/Spry1+ (more )
Structure Level Pattern Image Note
TS28: mammary gland epithelium Present Regionally restricted 1F Expression is in the branching epithelial network.
TS28: blood vessel Present Regionally restricted 1F Expression is in blood vessels of the mammary gland.
Specimen 1G: postnatal week 5; Spry1tm2Jdli/Spry1+ (more )
Structure Cell Type Level Pattern Image Note
TS28: mammary gland duct basal cell Present 1G Expression is in periductal fibroblasts, basal cells, and cap cells.
TS28: mammary gland duct fibroblast of mammary gland Present 1G Expression is in periductal fibroblasts, basal cells, and cap cells.
TS28: mammary gland epithelium Present Regionally restricted 1G Expression is in the basal ductal epithelium.
TS28: mammary gland luminal epithelium Weak 1G
Specimen 1H: postnatal week 5; Spry1tm2Jdli/Spry1+ (more )
Structure Cell Type Level Pattern Image Note
TS28: mammary duct terminal end bud basal cell Present 1H Expression is in periductal fibroblasts, basal cells, and cap cells.
TS28: mammary duct terminal end bud fibroblast of mammary gland Present 1H Expression is in periductal fibroblasts, basal cells, and cap cells.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory