Gene Expression Data
Assay Details
|
Assay
|
|
Reference:
|
J:181926
Jo HS, et al., Pten coordinates retinal neurogenesis by regulating Notch signalling. EMBO J. 2012 Feb 15;31(4):817-28
|
|
Assay type:
|
Immunohistochemistry
|
|
MGI Accession ID:
|
MGI:7764456
|
|
Gene symbol:
|
Crx
|
|
Gene name:
|
cone-rod homeobox
|
|
Antibody:
|
anti-Crx
|
|
Detection system:
|
Secondary antibody coupled to Cy3
|
|
|
Results
|
Specimen
3I Crx Pax6-aCre:
(close  )
|
Genetic Background:
|
Not Specified
|
|
Mutant Allele(s):
|
Tg(Pax6-cre,GFP)2Pgr/0
|
|
Age:
|
postnatal day 8
|
|
Sex:
|
Not Specified
|
|
Type:
|
optical section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: retina |
eye photoreceptor cell |
Present |
|
3I
|
|
Specimen
3J Crx Pten-cko:
(close )
|
Genetic Background:
|
involves: 129P2/OlaHsd
|
|
Mutant Allele(s):
|
Ptentm2Mak/Ptentm2Mak
Tg(Pax6-cre,GFP)2Pgr/0
|
|
Age:
|
postnatal day 8
|
|
Sex:
|
Not Specified
|
|
Type:
|
optical section
|
|
Fixation:
|
4% Paraformaldehyde
|
|
Embedding:
|
Cryosection
|
|
Note:
|
Conditional mutant.
|
| Structure |
Cell Type |
Level |
Pattern |
Image |
Note |
| TS28: retina |
eye photoreceptor cell |
Present |
Regionally restricted |
3J
|
Authors report ~27% increase in number of photoreceptor cells.
|
|
Analysis Tools
)
