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Gene Expression Data
Assay Details
Assay
Reference: J:171630 Bagheri-Fam S, et al., Defective survival of proliferating Sertoli cells and androgen receptor function in a mouse model of the ATR-X syndrome. Hum Mol Genet. 2011 Jun 1;20(11):2213-24
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7751458
Gene symbol: Amh
Gene name: anti-Mullerian hormone
Antibody: anti-AMH/MIS (C-20; sc-6886)
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 1A E14.5: embryonic day 14.5 (more )
Note: Double labeled: red - Amh; green - Atrx (assay MGI:7751460).
Structure Cell Type Level Pattern Image Note
TS22: Sertoli cell Sertoli cell Present 1A E14.5 Expressed in immature Sertoli cells.
Specimen 1A E17.5: embryonic day 17.5 (more )
Note: Double labeled: red - Amh; green - Atrx (assay MGI:7751460).
Structure Cell Type Level Pattern Image Note
TS25: Sertoli cell Sertoli cell Present 1A E17.5 Expressed in immature Sertoli cells.
Specimen 1Bii: embryonic day 14.5; Atrxtm1Rjg/Y, Plekha5Tg(AMH-cre)1Flor/0 (more )
Note: Conditional mutant. Double labeled: red - Amh; green - Atrx (assay MGI:7751460).
Structure Cell Type Level Pattern Image Note
TS22: Sertoli cell Sertoli cell Present 1Bii Expressed in immature Sertoli cells.
Specimen 2B Control: embryonic day 17.5; Atrxtm1Rjg/Y (more )
Structure Cell Type Level Pattern Image Note
TS25: Sertoli cell Sertoli cell Present 2B Control Expressed in immature Sertoli cells.
Specimen 2B cKO: embryonic day 17.5; Atrxtm1Rjg/Y, Plekha5Tg(AMH-cre)1Flor/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS25: Sertoli cell Sertoli cell Present 2B cKO Fewer testis cords than control, particularly in the core region.
Specimen not shown: embryonic day 15.5; Atrxtm1Rjg/Y (more )
Note: Quantified in Fig 3A.
Structure Cell Type Level Pattern Image Note
TS23: Sertoli cell Sertoli cell Present Expressed in immature Sertoli cells.
Specimen not shown: embryonic day 15.5; Atrxtm1Rjg/Y, Plekha5Tg(AMH-cre)1Flor/0 (more )
Note: Conditional mutant. Quantified in Fig 3A.
Structure Cell Type Level Pattern Image Note
TS23: Sertoli cell Sertoli cell Present Modest reduction (about 20%) in the number of Sertoli cells when compared with the control.
Specimen not shown: embryonic day 17.5; Atrxtm1Rjg/Y (more )
Note: Quantified in Fig 3A.
Structure Cell Type Level Pattern Image Note
TS25: Sertoli cell Sertoli cell Present Expressed in immature Sertoli cells. The number of Sertoli cells increases by 3.2-fold due to extensive proliferation.
Specimen not shown: embryonic day 17.5; Atrxtm1Rjg/Y, Plekha5Tg(AMH-cre)1Flor/0 (more )
Note: Conditional mutant. Quantified in Fig 3A.
Structure Cell Type Level Pattern Image Note
TS25: Sertoli cell Sertoli cell Present No increase was measured, and Sertoli cell numbers were 28% of control numbers.
Specimen 4A Control: embryonic day 15.5; Atrxtm1Rjg/Y (more )
Note: Double labeled: red - Amh; green - Casp3 (assay MGI:7751464).
Structure Cell Type Level Pattern Image Note
TS23: Sertoli cell Sertoli cell Present 4A left Expressed in immature Sertoli cells.
Specimen 4A cKO: embryonic day 15.5; Atrxtm1Rjg/Y, Plekha5Tg(AMH-cre)1Flor/0 (more )
Note: Conditional mutant. Double labeled: red - Amh; green - Casp3 (assay MGI:7751464).
Structure Cell Type Level Pattern Image Note
TS23: Sertoli cell Sertoli cell Present 4A right Expressed in immature Sertoli cells.
Specimen 5A Control: embryonic day 16.5; Atrxtm1Rjg/Y (more )
Note: Double labeled: red - Amh; green - PH3.
Structure Cell Type Level Pattern Image Note
TS24: Sertoli cell Sertoli cell Present 5A left Expressed in immature Sertoli cells.
Specimen 5A cKO: embryonic day 16.5; Atrxtm1Rjg/Y, Plekha5Tg(AMH-cre)1Flor/0 (more )
Note: Conditional mutant. Double labeled: red - Amh; green - PH3.
Structure Cell Type Level Pattern Image Note
TS24: Sertoli cell Sertoli cell Present 5A right The number of PH3-positive Sertoli cells increased by 38%, compared with the control.
Specimen 5B Control: embryonic day 16.5; Atrxtm1Rjg/Y (more )
Note: Double labeled: red - Amh; green - BrdU.
Structure Cell Type Level Pattern Image Note
TS24: Sertoli cell Sertoli cell Present 5B left Expressed in immature Sertoli cells.
Specimen 5B cKO: embryonic day 16.5; Atrxtm1Rjg/Y, Plekha5Tg(AMH-cre)1Flor/0 (more )
Note: Conditional mutant. Double labeled: red - Amh; green - BrdU.
Structure Cell Type Level Pattern Image Note
TS24: Sertoli cell Sertoli cell Present 5B right The number of BrdU-positive Sertoli cells was reduced by 13% compared with the control.
Specimen S6 P7 Control: postnatal day 7; Atrxtm1Rjg/Y (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present S6_P7 upper left Expressed in immature Sertoli cells.
Specimen S6 P7 cKO: postnatal day 7; Atrxtm1Rjg/Y, Plekha5Tg(AMH-cre)1Flor/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present S6_P7 upper right Expressed in immature Sertoli cells.
Specimen S6 P14 Control: postnatal day 14; Atrxtm1Rjg/Y (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Absent S6_P14 upper left No expression in mature Sertoli cells.
Specimen S6 P14 cKO: postnatal day 14; Atrxtm1Rjg/Y, Plekha5Tg(AMH-cre)1Flor/0 (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Absent S6_P14 upper right No expression in mature Sertoli cells, similar as in the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
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