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Gene Expression Data
Assay Details
Assay
Reference: J:74989 McEvilly RJ, et al., Transcriptional regulation of cortical neuron migration by POU domain factors. Science. 2002 Feb 22;295(5559):1528-32
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7751241
Gene symbol: Pou3f1
Gene name: POU domain, class 3, transcription factor 1
Antibody: anti-Tst-1
Results
Specimen S5C e18 WT: embryonic day 18.0 (more )
Structure Level Pattern Image Note
TS26: cortical plate Present Regionally restricted S5C e18 WT Expression layer V neurons in upper cortical plate.

Specimen S5C e18 Brn-1-/-: embryonic day 18.0; Pou3f3tm1Rmc/Pou3f3tm1Rmc (more )
Structure Level Pattern Image Note
TS26: cortical plate Present Regionally restricted S5C e18 Brn-1-/- Expression in upper cortical plate similar to wild type.

Specimen S5C P1 WT: postnatal day 1 (more )
Structure Level Pattern Image Note
TS27: cortical plate Present Regionally restricted S5C P1 WT Expression in neurons deeper in cortical plate.

Specimen S5C P1 Brn-1-/-: postnatal day 1; Pou3f3tm1Rmc/Pou3f3tm1Rmc (more )
Structure Level Pattern Image Note
TS27: cortical plate Present Regionally restricted S5C P1 Brn-1-/- Expression in neurons remaining in dorsal position, extending into marginal zone.

Specimen 5B WT: embryonic day 17.0 (more )
Structure Level Pattern Image Note
TS25: cortical plate Present Regionally restricted 5B Tst-1 WT Expression in neurons deeper in cortical plate.

Specimen 5B Brn-1-/-: embryonic day 17.0; Pou3f3tm1Rmc/Pou3f3tm1Rmc (more )
Structure Level Pattern Image Note
TS25: cortical plate Present Regionally restricted 5B Tst-1 Brn-1-/- Expression in neurons remaining in dorsal position, extending into marginal zone.

Specimen 5C Tst-1: postnatal day 0 (more )
Note: Double labeled: green - Pou3f1; red - Pou3f3 (assay MGI:7751233).
Structure Level Pattern Image Note
TS27: cortical layer V Present Regionally restricted 5C Tst-1/Brn-1 Expression colocalized with that of Pou3f3 in layer V neurons.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory