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Gene Expression Data
Assay Details
Assay
Reference: J:86692 Stenman JM, et al., Tlx controls proliferation and patterning of lateral telencephalic progenitor domains. J Neurosci. 2003 Nov 19;23(33):10568-76
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7738280
Gene symbol: Isl1
Gene name: ISL1 transcription factor, LIM/homeodomain
Antibody: anti-ISL1
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 4E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lateral ganglionic eminence subventricular zone Present 4E
TS22: corpus striatum Present Regionally restricted 4E Expression in differentiating cells.
Specimen 4F: embryonic day 14.5; Nr2e1tm1Rtyu/Nr2e1tm1Rtyu (more )
Structure Level Pattern Image Note
TS22: corpus striatum Present Regionally restricted 4F Expression is weaker and domain is reduced in size compared to wild type. Expression domain smaller than in both Tlx and Gsh1/Tlx mutants.
TS22: lateral ganglionic eminence subventricular zone Present Regionally restricted 4F Expression is weaker and domain is reduced in size compared to wild type. Expression domain smaller than in both Tlx and Gsh1/Tlx mutants.
Specimen 4G: embryonic day 14.5; Gsx2tm1Ssp/Gsx2tm1Ssp (more )
Structure Level Pattern Image Note
TS22: corpus striatum Present Regionally restricted 4G Fewer expressing cells are detected compared to wild type.
TS22: lateral ganglionic eminence subventricular zone Present Regionally restricted 4G Fewer expressing cells are detected compared to wild type.
Specimen 4H: embryonic day 14.5; Gsx2tm1Ssp/Gsx2tm1Ssp, Nr2e1tm1Rtyu/Nr2e1tm1Rtyu (more )
Structure Level Pattern Image Note
TS22: corpus striatum Present Regionally restricted 4H Fewer expressing cells are detected compared to wild type and single Gsh2 mutant.
TS22: lateral ganglionic eminence subventricular zone Present Regionally restricted 4H Fewer expressing cells are detected compared to wild type and single Gsh2 mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory