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Gene Expression Data
Assay Details
Assay
Reference: J:333327 Kurihara Y, et al., Mandibulofacial dysostosis with alopecia results from ETAR gain-of-function mutations via allosteric effects on ligand binding. J Clin Invest. 2023 Feb 15;133(4)
Assay type: RNA in situ
MGI Accession ID: MGI:7736650
Gene symbol: Dlx6
Gene name: distal-less homeobox 6
Probe: Dlx6 cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen WT-1: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component Present 2M WT left Dlx6
TS15: 1st branchial arch maxillary component Absent 2M WT left Dlx6
Specimen Y129F/+: embryonic day 9.5; Ednraem2Hku/Ednra+ (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component Present 2M Y129F/+ Dlx6
TS15: 1st branchial arch maxillary component Present 2M Y129F/+ Dlx6 Expression extended into the maxillary region in the mutant.
Specimen WT-2: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component Present 2M WT right Dlx6
TS15: 1st branchial arch maxillary component Absent 2M WT right Dlx6
Specimen E303K/+: embryonic day 9.5; Ednraem1Hku/Ednra+ (more )
Structure Level Pattern Image Note
TS15: 1st branchial arch mandibular component Present 2M E303K/+ Dlx6
TS15: 1st branchial arch maxillary component Present 2M E303K/+ Dlx6 Expression extended into the maxillary region in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory