Ednra^em1Hku
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ednra^em1Hku
• Name: endothelin receptor type A; endonuclease-mediated mutation 1, Hiroki Kurihara
• MGI ID: MGI:7736275
• Synonyms: Ednra^{em1(E303K)Hku}, ETAR_E303K
• Gene: Ednra Location: Chr8:78389658-78451081 bp, - strand Genetic Position: Chr8, 36.63 cM, cytoband C2
• Alliance: Ednra^em1Hku page

Mutation origin

• Strain of Origin: Crl:CD1

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutation: Single point mutation

Expression

In Mice Carrying this Mutation:

4 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ednra Mutation: 35 strains or lines available

References

• Original: J:333327 Kurihara Y, et al., Mandibulofacial dysostosis with alopecia results from ETAR gain-of-function mutations via allosteric effects on ligand binding. J Clin Invest. 2023 Feb 15;133(4)
• All: 1 reference(s)