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Gene Expression Data
Assay Details
Assay
Reference: J:170671 Shibata M, et al., MicroRNA-9 regulates neurogenesis in mouse telencephalon by targeting multiple transcription factors. J Neurosci. 2011 Mar 2;31(9):3407-22
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7736267
Gene symbol: Foxg1
Gene name: forkhead box G1
Antibody: Anti-Bf1
Detection system: Secondary antibody coupled to Alexa Fluor 594
Results
Specimen 2A miR-9-2 +/+; miR-9-3 +/+ E12.5: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Present 2A E12.5 left
Specimen 2A miR-9-2 -/-; miR-9-3 -/- E12.5: embryonic day 12.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Level Pattern Image Note
TS20: cerebral cortex ventricular layer Present 2A E12.5 right Expression of the Foxg1 protein increased in the double mutant ventricular zone compared to wild type.
Specimen 2A miR-9-2 +/+; miR-9-3 +/+ E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: cerebral cortex ventricular layer Present 2A E13.5 left
Specimen 2A miR-9-2 -/-; miR-9-3 -/- E13.5: embryonic day 13.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Level Pattern Image Note
TS21: cerebral cortex ventricular layer Present 2A E13.5 right Expression of the Foxg1 protein increased in the double mutant ventricular zone compared to wild type.
Specimen 2A miR-9-2 +/+; miR-9-3 +/+ E14.5: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 2A E14.5 left
Specimen 2A miR-9-2 -/-; miR-9-3 -/- E14.5: embryonic day 14.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Level Pattern Image Note
TS22: cerebral cortex ventricular layer Present 2A E14.5 right Expression of the Foxg1 protein increased in the double mutant ventricular zone compared to wild type.
Specimen 2A miR-9-2 +/+; miR-9-3 +/+ E16.5: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: cerebral cortex ventricular layer Present 2A E16.5 left
Specimen 2A miR-9-2 -/-; miR-9-3 -/- E16.5: embryonic day 16.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Level Pattern Image Note
TS24: cerebral cortex ventricular layer Present 2A E16.5 right No increased expression was apparent in the double mutant ventricular zone at E16.5.
Specimen 9U top: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: subpallium Moderate 9U top Expression was modest in wild type.
Specimen 9U bottom: embryonic day 15.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Level Pattern Image Note
TS23: subpallium Strong 9U bottom Expression was enhanced in the double mutant.
Specimen S7G: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: lateral ganglionic eminence Present S7G
Specimen S7H: embryonic day 12.5; Mir9-2tm1Sia/Mir9-2tm1Sia, Mir9-3tm1Sia/Mir9-3tm1Sia (more )
Structure Level Pattern Image Note
TS20: lateral ganglionic eminence Present S7H There was no increase in expression in E12.5 miR-9-2/3 double mutant lateral ganglionic eminence.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory