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Gene Expression Data
Assay Details
Assay
Reference: J:332639 Rinta-Jaskari MM, et al., Temporally and Spatially Regulated Collagen XVIII Isoforms Are Involved in Ureteric Tree Development Via the TSP1-like Domain. Matrix Biol. 2023 Jan 6;
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7735110
Gene symbol: Krt8
Gene name: keratin 8
Antibody: TROMA 1
Results
Specimen 3a WT: embryonic day 12.5 (more )
Note: Double labeled: red - Krt8; green - Col18a1 (assay MGI:7735109).
Structure Level Pattern Image Note
TS20: primitive collecting duct Present 3a WT Expression in ureteric tree.

Specimen 3a -/-: embryonic day 12.5; Col18a1tm1Hms/Col18a1tm1Hms (more )
Note: Double labeled: red - Krt8; green - Col18a1 (assay MGI:7735109).
Structure Level Pattern Image Note
TS20: primitive collecting duct Present 3a Col18a1-/- Expression in ureteric tree.

Specimen 3a P1/P1: embryonic day 12.5; Col18a1tm1Pih/Col18a1tm1Pih (more )
Structure Level Pattern Image Note
TS20: primitive collecting duct Present 3a Col18a1 P1/P1 Expression in ureteric tree.

Specimen 3a P2/P2: embryonic day 12.5; Col18a1tm2Pih/Col18a1tm2Pih (more )
Structure Level Pattern Image Note
TS20: primitive collecting duct Present 3a Col18a1 P2/P2 Expression in ureteric tree.

Specimen 4a WT: embryonic day 15.5 (more )
Structure Level Pattern Image Note
TS23: collecting duct Present 4a WT Expression in ureteric tree.

Specimen 4a -/-: embryonic day 15.5; Col18a1tm1Hms/Col18a1tm1Hms (more )
Structure Level Pattern Image Note
TS23: collecting duct Present Regionally restricted 4a Col18a1-/- Authors report reduced branching compared to wild type.

Specimen 4a P1/P1: embryonic day 15.5; Col18a1tm1Pih/Col18a1tm1Pih (more )
Structure Level Pattern Image Note
TS23: collecting duct Present Regionally restricted 4a Col18a1 P1/P1 Authors report reduced branching compared to wild type.

Specimen 4a P2/P2: embryonic day 15.5; Col18a1tm2Pih/Col18a1tm2Pih (more )
Structure Level Pattern Image Note
TS23: collecting duct Present Regionally restricted 4a Col18a1 P2/P2 Authors report reduced branching compared to wild type.

Specimen S2a WT: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: ureteric bud Present S2a WT Branching of tubular tree comparable between wild type and Col18a1-/- mutants from E11.5 to E13.5

Specimen S2a -/-: embryonic day 11.5; Col18a1tm1Hms/Col18a1tm1Hms (more )
Structure Level Pattern Image Note
TS19: ureteric bud Present S2a Col18a1-/- Branching of tubular tree comparable between wild type and Col18a1-/- mutants from E11.5 to E13.5

Specimen S2c WT: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: primitive collecting duct Present S2c WT Branching of tubular tree comparable between wild type and Col18a1-/- mutants from E11.5 to E13.5

Specimen S2c -/-: embryonic day 12.5; Col18a1tm2Pih/Col18a1tm2Pih (more )
Structure Level Pattern Image Note
TS20: primitive collecting duct Present S2c Col18a1-/- Branching of tubular tree comparable between wild type and Col18a1-/- mutants from E11.5 to E13.5

Specimen S2e WT: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: collecting duct Present S2e WT Branching of tubular tree comparable between wild type and Col18a1-/- mutants from E11.5 to E13.5

Specimen S2e -/-: embryonic day 13.5; Col18a1tm1Hms/Col18a1tm1Hms (more )
Structure Level Pattern Image Note
TS21: collecting duct Present S2e Col18a1-/- pBranching of tubular tree comparable between wild type and Col18a1-/- mutants from E11.5 to E13.5

Specimen 7a: embryonic day 16.5 (more )
Note: Double labeled: green - Krt8; red - Itga3 (assay MGI:7735115).
Structure Level Pattern Image Note
TS24: collecting duct Present Regionally restricted 7a Expression overlapped with that of Itga3 in branching tubules.

Specimen 7b: embryonic day 16.5 (more )
Note: Double labeled: green - Krt8; red - Col18a1 (assay MGI:7735109).
Structure Level Pattern Image Note
TS24: collecting duct Present Regionally restricted 7b Expression overlapped with that of Col18a1 in branching tubules.

Specimen 7c: embryonic day 16.5; Col18a1tm1Hms/Col18a1tm1Hms (more )
Note: Double labeled: green - Krt8; red - Itga3 (assay MGI:7735115).
Structure Level Pattern Image Note
TS24: collecting duct Present Regionally restricted 7c Expression overlapped with that of Itga3 in branching tubules.

Specimen 7d: embryonic day 16.5; Col18a1tm1Hms/Col18a1tm1Hms (more )
Note: Double labeled: green - Krt8; red - Col18a1 (assay MGI:7735109).
Structure Level Pattern Image Note
TS24: collecting duct Present Regionally restricted 7d Expression overlapped with that of Col18a1 in branching tubules.


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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory